Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341961 | 0.86 | APEX1 (0.71) | APEX1CDK2KDM4ETDP1KCNK2 | |
| SCHEMBL20563146 | 0.83 | APEX1 (0.50) | APEX1ACLYCDK2KDM4ETDP1 | |
| SCHEMBL18967222 | 0.82 | APEX1 (0.40) | APEX1ACLYCDK2KDM4ETDP1 | |
| SCHEMBL5054548 | 0.81 | KDM4E (0.47) | KDM4EAGTR1RAB9APOLBAKR1C3 | |
| SCHEMBL23534118 | 0.80 | KDM4C (0.55) | APEX1ACLYCDK2KDM4ETDP1 | |
| SCHEMBL9744548 | 0.79 | CLCN2 (0.46) | KDM4ETDP1KCNK2GRIK1AGTR1 | |
| SCHEMBL3236365 | 0.79 | ALDH1A1 (0.58) | KDM4EGRIK1RAB9AMEN1KMT2A | |
| SCHEMBL25235960 | 0.79 | KDM6B (0.56) | APEX1ACLYCDK2KDM4ETDP1 | |
| SCHEMBL25870114 | 0.79 | APEX1 (0.54) | APEX1ACLYCDK2KDM4ETDP1 | |
| SCHEMBL8362077 | 0.79 | APEX1 (0.45) | APEX1CDK2KDM4ETDP1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999050438-A2 | CHROMOGENIC INDOLE DERIVATIVES | INALCO S.P.A. (IT) | 1999-10-07 | — | — | WO | disclosed |