SCHEMBL8368157

SCHEMBL8368157

CO[C@H]1[C@H](O)[C@@H](CO)O[CH][C@@H]1O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 7/20 0.36
OGA O60502 1/20 0.35
PYGB P11216 1/20 0.31
SLC2A1 P11166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1870755 1.00 LGALS8 (0.36) LGALS8OGAPYGBSLC2A1
SCHEMBL1979122 0.85 LGALS8 (0.33) LGALS8OGAPYGB
SCHEMBL11168480 0.83 LGALS8 (0.39) LGALS8OGAPYGB
SCHEMBL5183891 0.77
SCHEMBL393237 0.77
SCHEMBL3623222 0.77
SCHEMBL532553 0.77
SCHEMBL1607814 0.77
SCHEMBL37974 0.77
SCHEMBL532554 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104780927-A Transglutaminase activator KAO CORP 2015-07-15 CN claimed
CN-103313696-A Skin whitening agent KAO CORP 2013-09-18 CN claimed
CN-103313696-B whitening agent KAO CORP. (JP) 2016-05-18 CN disclosed
CN-103313696-A Skin whitening agent KAO CORP 2013-09-18 CN disclosed
EP-0641327-B1 NOVEL ALPHA-MANNOSIDASE INHIBITORS MERRELL PHARMA INC (US) 1999-01-20 EP disclosed
EP-0451834-B1 Alpha-mannosidase and fucosidase inhibitors MERRELL PHARMA INC (US) 1996-07-24 EP disclosed
US-5438069-A Glucohydrolase inhibitors useful as antidiabetic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1995-08-01 US disclosed
EP-0641327-A1 NOVEL ALPHA-MANNOSIDASE INHIBITORS MERRELL PHARMACEUTICALS INC. (US) 1995-03-08 EP disclosed
US-5382709-A IMMUNOSTIMULANTS, VIRICIDES AND ANTIMETASTATIC AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1995-01-17 US disclosed
EP-0297534-B1 Castanospermine esters and glycosides MERRELL DOW PHARMA (US) 1994-12-28 EP disclosed
US-5262425-A Immunostimulants, chemoprotective and radioprotective agents, antimetastatic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1993-11-16 US disclosed
US-5240707-A 2,3,4-trihydroxy-5-(hydroxymethyl)cyclopentylamines used as immunostimulants, viricides and antimetastasis agents MERRELL DOW PHARMACEUTICALS INC. 1993-08-31 US disclosed
WO-1993005781-A1 NOVEL ALPHA-MANNOSIDASE INHIBITORS MERRELL DOW PHARMACEUTICALS INC. (US) 1993-04-01 WO disclosed
WO-1992011867-A1 NOVEL GLUCOHYDROLASE INHIBITORS USEFUL AS ANTIDIABETIC AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1992-07-23 WO disclosed
EP-0451834-A2 Alpha-mannosidase and fucosidase inhibitors MERRELL PHARMACEUTICALS INC. (US) 1991-10-16 EP disclosed
US-5017563-A Antidiabetic MERRELL DOW PHARMACEUTICALS INC. (US) 1991-05-21 US disclosed
EP-0297534-A2 Castanospermine esters and glycosides MERRELL DOW PHARMACEUTICALS INC. (US) 1989-01-04 EP disclosed