Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368228 | 1.00 | HIF1A (0.47) | HIF1AMAPTTDP1PPARGLMNA | |
| SCHEMBL8780082 | 1.00 | HIF1A (0.47) | HIF1AMAPTTDP1PPARGLMNA | |
| SCHEMBL8780118 | 0.87 | HIF1A (0.51) | HIF1APDCD1CD274 | |
| SCHEMBL8370701 | 0.87 | HIF1A (0.51) | HIF1APDCD1CD274 | |
| SCHEMBL8370696 | 0.87 | HIF1A (0.51) | HIF1APDCD1CD274 | |
| SCHEMBL7566354 | 0.85 | HIF1A (0.48) | HIF1AMAPTPDCD1CD274 | |
| SCHEMBL8372363 | 0.85 | HIF1A (0.48) | HIF1AMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL8780047 | 0.85 | HIF1A (0.48) | HIF1AMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL8372364 | 0.85 | HIF1A (0.48) | HIF1AMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL7566352 | 0.85 | HIF1A (0.48) | HIF1AMAPTPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5770614-A | EXCELLENT ACTIVITY OF CONTROLLING PSEUDOCERCOSPORELLA HERPOTRICHOIDES | SHIONOGI & CO., LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5506358-A | USEFUL AS AGRICULTURAL FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |