SCHEMBL8368296

SCHEMBL8368296

CCCCCCCCCCCCCCCCC(O)CN(C)CC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 8/20 0.58
FFAR1 O14842 3/20 0.56
FFAR4 Q5NUL3 2/20 0.56
FAAH O00519 2/20 0.46
NFKB1 P19838 1/20 0.42
MAPT P10636 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
GRIK1 P39086 1/20 0.40
GRIK2 Q13002 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8365417 1.00 GPR84 (0.58) GPR84FFAR1FFAR4FAAHNFKB1
SCHEMBL11582327 1.00 GPR84 (0.58) GPR84FFAR1FFAR4FAAHNFKB1
SCHEMBL10542115 0.84 GPR84 (0.59) GPR84FFAR1FFAR4FAAHNFKB1
SCHEMBL26125681 0.84 GPR84 (0.46) GPR84FFAR1FFAR4MAPTLCK
SCHEMBL14906270 0.84 GPR84 (0.59) GPR84FFAR1FFAR4FAAHNFKB1
SCHEMBL6829184 0.83 GPR84 (0.50) GPR84FFAR1FFAR4NFKB1
SCHEMBL17750773 0.83 GPR84 (0.50) GPR84FFAR1FFAR4NFKB1
SCHEMBL11456950 0.83 GPR84 (0.50) GPR84FFAR1FFAR4NFKB1
SCHEMBL11464857 0.83 GPR84 (0.50) GPR84FFAR1FFAR4NFKB1
SCHEMBL10871527 0.82 FFAR4 (0.65) GPR84FFAR1FFAR4PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0710482-B1 Therapeutic agent for myocardial ischemic damages or reperfusion injuries KOWA CO (JP) 1999-01-07 EP claimed
EP-0786254-A1 PREVENTIVE OR REMEDY FOR KIDNEY DISEASES KOWA CO. LTD. (JP) 1997-07-30 EP claimed
EP-0728173-B1 USE OF AN AMPHOTERIC SURFACTANT AS A FRICTION-REDUCING AGENT BEROL NOBEL AB (SE) 1999-01-07 EP disclosed
US-5700766-A STABILIZING THE WATER FLOW BY MIXING A LOW MOLECULAR WEIGHT HEAT RESISTANT HYDROCARBON ONE OR POLYCARBOXY GROUPS WITH ONE OR POLY-TERTIARY AMINE GROUPS, AMIDE GROUPS OR IMIDE GROUPS BEROL NOBEL AB (SE) 1997-12-23 US disclosed
EP-0786254-A1 PREVENTIVE OR REMEDY FOR KIDNEY DISEASES KOWA CO. LTD. (JP) 1997-07-30 EP disclosed
EP-0728173-A1 USE OF AN AMPHOTERIC SURFACTANT AS A FRICTION-REDUCING AGENT Berol Nobel AB (SE) 1996-08-28 EP disclosed
WO-1995011288-A1 USE OF AN AMPHOTERIC SURFACTANT AS A FRICTION-REDUCING AGENT BEROL NOBEL AB (SE) 1995-04-27 WO disclosed
EP-0186083-A2 N-(2-Hyxdroxyalkyl)-amino acids and their derivatives, process for their preparation and pharmaceutical compositions containing them ASTA Pharma AG (DE) 1986-07-02 EP disclosed
US-4161603-A HEAT RESISTANT POLYESTERS CIBA-GEIGY CORPORATION (US) 1979-07-17 US disclosed
US-4122276-A FOR MAKING CONDENSATION POLYMERS CONTAINING HYDANTOIN CIBA-GEIGY CORPORATION (US) 1978-10-24 US disclosed
US-4085243-A FABRIC SOFTENER, SOIL RELEASE AGENT COLGATE-PALMOLIVE COMPANY (US) 1978-04-18 US disclosed
US-3965014-A POLYDIMETHYL SILOXANE, SURFACTANT COLGATE-PALMOLIVE COMPANY (US) 1976-06-22 US disclosed