SCHEMBL8368307

SCHEMBL8368307

CNC(=O)/C(=N\OC)c1ccccc1/C=C/c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NFE2L2 Q16236 2/20 0.41
TRPA1 O75762 2/20 0.41
CAPN1 P07384 1/20 0.40
BACE1 P56817 1/20 0.39
SNCA P37840 3/20 0.38
ALDH1A1 P00352 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
HIF1A Q16665 1/20 0.36
CMA1 P23946 1/20 0.36
NPC1 O15118 2/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368311 1.00 CYP1A2 (0.41) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL8369609 1.00 CYP1A2 (0.41) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL8368312 1.00 CYP1A2 (0.41) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL8369611 1.00 CYP1A2 (0.41) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL8369607 1.00 CYP1A2 (0.41) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL8368309 1.00 CYP1A2 (0.41) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL8954615 0.86 HIF1A (0.47) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL10433779 0.84 ALDH1A1 (0.44) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL10433781 0.84 ALDH1A1 (0.44) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1
SCHEMBL10433782 0.84 ALDH1A1 (0.44) CYP1A2CYP2C19HSD17B10NFE2L2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617011-B1 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO (JP) 1999-01-20 EP disclosed
EP-0398692-B1 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI & CO (JP) 1996-08-21 EP disclosed
US-5548078-A FOR AGRICULTURE SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-08-20 US disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
US-5401877-A Agricultural fungicide SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-28 US disclosed
EP-0629609-A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-12-21 EP disclosed
US-5371223-A Controlling phytopathogens SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5371222-A Intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed