Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PRF1 | P14222 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24060998 | 0.92 | MAPT (0.39) | HDAC6HSD17B1MAPTSMN1; SMN2STK17B | |
| SCHEMBL21797211 | 0.92 | MAPT (0.39) | HDAC6HSD17B1MAPTSMN1; SMN2STK17B | |
| SCHEMBL28337823 | 0.89 | HDAC1 (0.42) | HDAC6SMN1; SMN2PLA2G10ALDH1A1 | |
| SCHEMBL26770810 | 0.86 | PLA2G10 (0.40) | MAPTPLA2G10KDM4EPOLBNPC1 | |
| SCHEMBL3472776 | 0.83 | ESR2 (0.46) | HDAC6HSD17B1 | |
| SCHEMBL5466664 | 0.83 | ESR1 (0.36) | HSD17B1PLA2G10 | |
| SCHEMBL23246441 | 0.82 | PLA2G10 (0.41) | HDAC6MAPTSMN1; SMN2PLA2G10ALDH1A1 | |
| SCHEMBL15255594 | 0.81 | PLA2G10 (0.42) | MAPTSMN1; SMN2PLA2G10ALDH1A1KDM4E | |
| SCHEMBL20527880 | 0.80 | APP (0.39) | MAPTSMN1; SMN2PRF1PLA2G10ALDH1A1 | |
| SCHEMBL26770808 | 0.80 | PLA2G10 (0.38) | MAPTPLA2G10KDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11255764-A | — | — | None | — | — | JP | disclosed |
| JP-H11255764-A | PHOTOCHROMIC CRYSTAL MATERIAL | JAPAN SCIENCE & TECHNOLOGY CORP | 1999-09-21 | — | — | JP | disclosed |