SCHEMBL3472776

SCHEMBL3472776

Cc1sc(-c2ccc(O)cc2)cc1C1=C(c2cc(-c3ccc(O)cc3)sc2C)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 7/20 0.46
ESR1 P03372 6/20 0.46
HSD17B1 P14061 6/20 0.40
HSD17B2 P37059 6/20 0.40
APP P05067 7/20 0.39
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13164291 0.94 ESR1 (0.42) ESR2ESR1HSD17B1HSD17B2APP
SCHEMBL9034401 0.92 GSK3B (0.41) ESR2ESR1HSD17B1HSD17B2APP
SCHEMBL5466664 0.88 ESR1 (0.36) ESR2ESR1HSD17B1HSD17B2
SCHEMBL20527880 0.85 APP (0.39) APP
SCHEMBL423920 0.84 PLA2G10 (0.41) ESR2ESR1HSD17B1HSD17B2
SCHEMBL20089641 0.84 PRF1 (0.34) ESR2ESR1HSD17B1HSD17B2
SCHEMBL14838354 0.83 ESR1 (0.65) ESR2ESR1HSD17B1HSD17B2APP
SCHEMBL28337823 0.83 HDAC1 (0.42) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL8368346 0.83 HDAC6 (0.44) HSD17B1HDAC6
SCHEMBL6735028 0.82 APP (0.40) HSD17B1HSD17B2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2408572-B1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORP (US) 2016-12-21 EP disclosed
EP-2403656-B1 ELECTRONIC DEVICES COMPRISING A STRUCTURED ORGANIC FILM XEROX CORP (US) 2016-12-07 EP disclosed
US-9097995-B2 Electronic devices comprising structured organic films XEROX CORPORATION (US) 2015-08-04 US disclosed
US-9097995-B2 Electronic devices comprising structured organic films XEROX CORPORATION (US) 2015-08-04 US disclosed
US-20130137033-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORPORATION (US) 2013-05-30 US disclosed
US-20130137033-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORPORATION (US) 2013-05-30 US disclosed
US-8415472-B2 Water soluble photochromic compounds for labeling of biomolecules and method for detecting biomolecules using the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-04-09 US disclosed
US-8415472-B2 Water soluble photochromic compounds for labeling of biomolecules and method for detecting biomolecules using the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-04-09 US disclosed
US-8394495-B2 Composite structured organic films XEROX CORPORATION (US) 2013-03-12 US disclosed
US-8394495-B2 Composite structured organic films XEROX CORPORATION (US) 2013-03-12 US disclosed
US-20100227071-A1 PROCESS FOR PREPARING STRUCTURED ORGANIC FILMS (SOFS) VIA A PRE-SOF XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227157-A1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100227157-A1 COMPOSITE STRUCTURED ORGANIC FILMS XEROX CORPORATION (US) 2010-09-09 US disclosed
WO-2007075951-A2 METHODS FOR STORING HOLOGRAPHIC DATA AND ARTICLES HAVING ENHANCED DATA STORAGE LIFETIME DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2007-07-05 WO disclosed
US-20070147214-A1 Methods for storing holographic data and articles having enhanced data storage lifetime derived therefrom GENERAL ELECTRIC COMPANY (US) 2007-06-28 US disclosed
US-20070147214-A1 Methods for storing holographic data and articles having enhanced data storage lifetime derived therefrom GENERAL ELECTRIC COMPANY (US) 2007-06-28 US disclosed
US-20070147214-A1 Methods for storing holographic data and articles having enhanced data storage lifetime derived therefrom GENERAL ELECTRIC COMPANY (US) 2007-06-28 US disclosed
US-20070097469-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-05-03 US disclosed
US-20070097469-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-05-03 US disclosed
US-20070097469-A1 Methods for making holographic data storage articles GENERAL ELECTRIC COMPANY (US) 2007-05-03 US disclosed