Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.44 |
| ▸ | XPO1 | O14980 | 3/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368479 | 1.00 | HIF1A (0.44) | HIF1AXPO1PTK2MRGPRX4JAK2 | |
| SCHEMBL8780136 | 1.00 | HIF1A (0.44) | HIF1AXPO1PTK2MRGPRX4JAK2 | |
| SCHEMBL8645605 | 0.89 | HIF1A (0.44) | HIF1APTK2SGMS2FLT4MAOA | |
| SCHEMBL8645609 | 0.89 | HIF1A (0.44) | HIF1APTK2SGMS2FLT4MAOA | |
| SCHEMBL8371571 | 0.89 | HIF1A (0.44) | HIF1APTK2JAK2NTRK1KDR | |
| SCHEMBL8371570 | 0.89 | HIF1A (0.44) | HIF1APTK2JAK2NTRK1KDR | |
| SCHEMBL8372643 | 0.87 | HIF1A (0.43) | HIF1ASGMS2FLT4MAOAMAOB | |
| SCHEMBL8372644 | 0.87 | HIF1A (0.43) | HIF1ASGMS2FLT4MAOAMAOB | |
| SCHEMBL8369594 | 0.85 | HIF1A (0.42) | HIF1ASGMS2FLT4MAOAMAOB | |
| SCHEMBL8369593 | 0.85 | HIF1A (0.42) | HIF1ASGMS2FLT4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617011-B1 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |
| US-5770614-A | EXCELLENT ACTIVITY OF CONTROLLING PSEUDOCERCOSPORELLA HERPOTRICHOIDES | SHIONOGI & CO., LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| US-5506358-A | USEFUL AS AGRICULTURAL FUNGICIDES | SHIONOGI & CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0617011-A2 | Process for producing alkoxyiminoacetamide compounds | SHIONOGI & CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |