SCHEMBL8369593

SCHEMBL8369593

CNC(=O)/C(=N\OC)c1ccccc1COc1ccc(C(F)(F)F)c(OC(C)C)n1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.42
SGMS2 Q8NHU3 1/20 0.33
FLT4 P35916 1/20 0.33
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
OPRL1 P41146 1/20 0.31
PDCD1 Q15116 2/20 0.30
CD274 Q9NZQ7 2/20 0.30
PTGES O14684 2/20 0.30
RBP4 P02753 1/20 0.30
SLC13A5 Q86YT5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8369594 1.00 HIF1A (0.42) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8372658 0.93 HIF1A (0.42) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8372656 0.93 HIF1A (0.42) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8371570 0.91 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8371571 0.91 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8370581 0.87 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8370584 0.87 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8368479 0.85 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8645609 0.85 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB
SCHEMBL8780136 0.85 HIF1A (0.44) HIF1ASGMS2FLT4MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617011-B1 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO (JP) 1999-01-20 EP disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed