⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437253 | 0.75 | — | — | |
| SCHEMBL9380203 | 0.67 | — | — | |
| SCHEMBL21800420 | 0.64 | PNMT (0.44) | — | |
| SCHEMBL31111348 | 0.63 | PNMT (0.43) | — | |
| SCHEMBL7793899 | 0.62 | — | — | |
| SCHEMBL3144398 | 0.62 | — | — | |
| SCHEMBL371880 | 0.62 | — | — | |
| SCHEMBL156559 | 0.62 | — | — | |
| SCHEMBL667084 | 0.62 | — | — | |
| SCHEMBL16320462 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877720-B2 | Epirubicin derivatives | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2014-11-04 | — | — | US | claimed |
| US-20130131001-A1 | Epirubicin Derivatives | Tianjin Michele Sci-Tech Development Co., (CN) | 2013-05-23 | — | — | US | claimed |
| EP-3592730-B1 | PRODRUGS OF SULFASALAZINE, PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE DISEASE | TRULY TRANSLATIONAL SWEDEN AB (SE) | 2021-08-04 | — | — | EP | disclosed |
| US-10703723-B2 | Prodrugs of sulfasalazine, pharmaceutical compositions thereof and their use in the treatment of autoimmune disease | TRULY TRANSLATIONAL SWEDEN AB (SE) | 2020-07-07 | — | — | US | disclosed |
| WO-2018162625-A1 | PRODRUGS OF SULFASALAZINE, PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE DISEASE | TRULY TRANSLATIONAL SWEDEN AB (SE) | 2018-09-13 | — | — | WO | disclosed |
| US-9040516-B2 | Uracil derivative and use thereof for medical purposes | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-8877720-B2 | Epirubicin derivatives | TIANJIN HEMAY BIO-TECH CO., LTD. (CN) | 2014-11-04 | — | — | US | disclosed |
| US-20140179670-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| EP-2740728-A1 | URACIL DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2014-06-11 | — | — | EP | disclosed |
| US-20130131001-A1 | Epirubicin Derivatives | Tianjin Michele Sci-Tech Development Co., (CN) | 2013-05-23 | — | — | US | disclosed |
| EP-0888372-A1 | OLIGONUCLEOTIDE-ANTHRACYCLINE AND OLIGONUCLEOTIDE-ANTHRACYCLINONE CONJUGATES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997011370-A1 | RECOMBINANT PROTEINS HAVING MULTIPLE DISULFIDE BONDS AND THIOL-SUBSTITUTED CONJUGATES THEREOF | IMMUNOMEDICS, INC. (US) | 1997-03-27 | — | — | WO | disclosed |
| EP-0274174-B1 | LIPOSOME/ANTHRAQUINONE DRUG COMPOSITION AND METHOD | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1992-11-04 | — | — | EP | disclosed |
| US-5043166-A | Antitumor agents; side effect reduction | HADASIT MEDICAL RESEARCH, INC. (IL) | 1991-08-27 | — | — | US | disclosed |
| US-4898735-A | Liposome/doxorubicin composition and method | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1990-02-06 | — | — | US | disclosed |
| US-4797285-A | ANTIBIOTICS, FERRIOXAMINE | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1989-01-10 | — | — | US | disclosed |
| EP-0274174-A1 | Liposome/anthraquinone drug composition and method | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1988-07-13 | — | — | EP | disclosed |
| US-4585859-A | ANTITUMOR AGENTS | SRI INTERNATIONAL (US) | 1986-04-29 | — | — | US | disclosed |
| EP-0128670-A1 | 4-Demethoxy-3'-deamino-3'(4-morpholinyl) derivatives of anthracycline anticancer antibiotics | ADRIA LABORATORIES, INC. (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4464529-A | ANTITUMOR AGENTS | SRI INTERNATIONAL (US) | 1984-08-07 | — | — | US | disclosed |