1,4-Dichlorobenzene

1,4-Dichlorobenzene

SCHEMBL8368501

Clc1ccc(Cl)cc1.S.S.[NaH]

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.80
CYP2A6 P11509 1/20 0.80
IDO1 P14902 2/20 0.53
TSHR P16473 5/20 0.50
CYP1A2 P05177 1/20 0.47
MAPK1 P28482 4/20 0.44
CYP3A4 P08684 2/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
ENPP2 Q13822 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HIF1A Q16665 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TP53 P04637 2/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL11593739 0.95 LMNA (0.89) LMNACYP2A6IDO1TSHRCYP1A2
1,4-Dichlorobenzene SCHEMBL6228832 0.95
1,4-Dichlorobenzene SCHEMBL28177733 0.95
1,4-Dichlorobenzene SCHEMBL11243685 0.89
1,4-Dichlorobenzene SCHEMBL5191 0.89
1,4-Dichlorobenzene SCHEMBL6230506 0.84
1,4-Dichlorobenzene SCHEMBL8166345 0.84
1,4-Dichlorobenzene SCHEMBL6534336 0.84
1,4-Dichlorobenzene SCHEMBL5144812 0.84 LMNA (0.89) LMNACYP2A6IDO1TSHRCYP1A2
1,4-Dichlorobenzene SCHEMBL11577097 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11005990-A None JP disclosed
JP-H115990-A PRODUCTION OF SLIDING BEARING MADE FROM SYNTHETIC RESIN NTN CORP 1999-01-12 JP disclosed