SCHEMBL8368641

SCHEMBL8368641

CCCCCCC(CCCCCC)[SiH](OC)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.44
GPR84 Q9NQS5 6/20 0.40
SPHK1 Q9NYA1 2/20 0.40
FFAR1 O14842 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
CYP2D6 P10635 2/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CETP P11597 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6659131 1.00 DNM1 (0.44) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL29040555 0.98 DNM1 (0.48) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL7907618 0.95 DNM1 (0.44) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL6298249 0.91 DNM1 (0.41) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL6303331 0.91 DNM1 (0.41) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL28015352 0.91 DNM1 (0.41) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL8470115 0.90 DNM1 (0.42) DNM1LMNATSHRCYP3A4
SCHEMBL2948947 0.90 DNM1 (0.37) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL27812172 0.88 DNM1 (0.37) DNM1GPR84SPHK1FFAR1ZDHHC7
SCHEMBL8469017 0.86 DNM1 (0.39) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0576413-B1 Electron donors for improved olefin polymerization FINA TECHNOLOGY (US) 1999-01-13 EP disclosed