SCHEMBL8368698

SCHEMBL8368698

CC(CC(c1ccccc1)c1ccc(O)c(S(=O)(=O)O)c1O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.42
SIRT1 Q96EB6 4/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
CHRM2 P08172 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
HRH1 P35367 2/20 0.36
ESR1 P03372 1/20 0.36
CHRM4 P08173 1/20 0.36
KCNE1 P15382 1/20 0.36
PTGS1 P23219 1/20 0.36
HRH2 P25021 1/20 0.36
HTR2A P28223 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRK1 P41145 1/20 0.36
KCNQ1 P51787 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368366 0.89 TRPA1 (0.40) TRPA1SIRT1SIRT2LMNAMAPT
SCHEMBL8367498 0.88 TRPA1 (0.41) TRPA1LMNAMAPTDAPK1TAAR1
SCHEMBL8365859 0.87 TRPA1 (0.43) TRPA1LMNAMAPTCHRM2CHRM5
SCHEMBL8367636 0.87 TRPA1 (0.38) TRPA1SIRT1SIRT2LMNAMAPT
SCHEMBL8914597 0.86 TRPA1 (0.43) TRPA1LMNAMAPTCHRM3PTGS1
SCHEMBL8367586 0.84 TRPA1 (0.40) TRPA1LMNAMAPTCHRM2CHRM5
SCHEMBL8367499 0.82 TYR (0.49) SIRT1SIRT2LMNAMAPTCHRM2
SCHEMBL8367578 0.82 TRPA1 (0.38) TRPA1LMNAMAPTCHRM2CHRM5
SCHEMBL8370456 0.81 TRPA1 (0.38) TRPA1LMNAMAPTCHRM2CHRM5
SCHEMBL8370490 0.80 TYR (0.46) SIRT1SIRT2LMNAMAPTCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed