Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314975 | 0.88 | GRIA1 (0.82) | GRIA1 | |
| SCHEMBL8367567 | 0.84 | GRIA1 (0.75) | GRIA1 | |
| SCHEMBL8367555 | 0.84 | GRIA1 (0.80) | GRIA1 | |
| SCHEMBL678000 | 0.83 | GRIA1 (1.00) | GRIA1 | |
| SCHEMBL29542563 | 0.83 | GRIA1 (1.00) | GRIA1 | |
| SCHEMBL31562972 | 0.80 | GRIA1 (0.84) | GRIA1 | |
| SCHEMBL12049626 | 0.80 | GRIA1 (0.84) | GRIA1 | |
| SCHEMBL8367564 | 0.80 | GRIA1 (0.69) | GRIA1 | |
| SCHEMBL8367101 | 0.78 | GRIA1 (0.67) | GRIA1 | |
| SCHEMBL8366785 | 0.77 | GRIA1 (0.69) | GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799913-B2 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | CORTEX PHARMACEUTICALS, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7799913-B2 | Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses | CORTEX PHARMACEUTICALS, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| WO-2003045315-A2 | CARBONYLBENZOXAZINE COMPOUNDS FOR ENHANCING GLUTAMATERGIC SYNAPTIC RESPONSES | CORTEX PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |