Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16059320 | 1.00 | TSHR (0.64) | TSHRALDH1A1LMNAGAAKMT2A | |
| SCHEMBL14424555 | 0.92 | DGKA (0.59) | TSHRALDH1A1LMNAKMT2ADGKA | |
| SCHEMBL20210514 | 0.92 | TSHR (0.54) | TSHRALDH1A1LMNAGAADGKA | |
| SCHEMBL5034229 | 0.92 | TSHR (0.54) | TSHRALDH1A1LMNAGAAKMT2A | |
| SCHEMBL4430084 | 0.90 | TSHR (0.70) | TSHRALDH1A1LMNAGAAKMT2A | |
| SCHEMBL26118353 | 0.90 | TSHR (0.52) | TSHRALDH1A1LMNAGAAKMT2A | |
| SCHEMBL6424609 | 0.89 | TSHR (0.56) | TSHRALDH1A1LMNAGAAKMT2A | |
| SCHEMBL20210561 | 0.89 | TSHR (0.56) | TSHRALDH1A1LMNAKMT2ADGKA | |
| SCHEMBL8432325 | 0.89 | TSHR (0.56) | TSHRALDH1A1LMNADGKARECQL | |
| SCHEMBL9741785 | 0.89 | TSHR (0.56) | TSHRALDH1A1LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052922-A1 | ANTIMICROBIAL βGalNAc(1→4)βGal DERIVATIVES AND METHODS OF USE | HELIX BIOPHARMA CORP. (CA) | 1999-10-21 | — | — | WO | disclosed |