Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Danthron. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | MAOA | P21397 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | MAOB | P27338 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | RECQL | P46063 | 5/20 | 0.69 |
| ▸ | ELANE | P08246 | 5/20 | 0.69 |
| ▸ | CTSG | P08311 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Danthron SCHEMBL29356886 | 1.00 | MAPT (1.00) | MAPTALDH1A1TDP1MAOATSHR | |
| Danthron SCHEMBL30544826 | 1.00 | MAPT (1.00) | MAPTALDH1A1TDP1MAOATSHR | |
| Danthron SCHEMBL20565674 | 0.98 | MAPT (0.95) | MAPTALDH1A1TDP1MAOATSHR | |
| Danthron SCHEMBL30721499 | 0.98 | MAPT (0.95) | MAPTALDH1A1TDP1MAOATSHR | |
| Anthrarufin SCHEMBL29874705 | 0.92 | MAOA (1.00) | MAPTALDH1A1TDP1MAOATSHR | |
| Anthrarufin SCHEMBL29363946 | 0.92 | MAOA (1.00) | MAPTALDH1A1TDP1MAOATSHR | |
| SCHEMBL875843 | 0.92 | MAPT (0.86) | MAPTALDH1A1TDP1MAOATSHR | |
| Anthrarufin SCHEMBL187843 | 0.92 | MAOA (1.00) | MAPTALDH1A1TDP1MAOATSHR | |
| Anthrarufin SCHEMBL25355428 | 0.91 | MAOA (0.86) | MAPTALDH1A1TDP1MAOATSHR | |
| 1-Hydroxyanthraquinone SCHEMBL145303 | 0.91 | MAOA (0.86) | MAPTALDH1A1TDP1MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4354 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250387524-A1 | METHOD AND SYSTEM FOR THE PRODUCTION OF DISINFECTION AND/OR STERILISATION SOLUTIONS | ESTEVEZ COMPANY CARLOS (ES) | 2025-12-25 | — | — | US | claimed |
| EP-4635489-A1 | COMPOSITION FOR PREVENTING OR TREATING SIDE EFFECTS OF CHOLINESTERASE INHIBITORS | Dr.Noah Biotech Inc. (KR) | 2025-10-22 | — | — | EP | claimed |
| US-20250262169-A1 | METHODS OF TREATING COENZYME Q10 DEFICIENCY | THLIVERIS, ANDREW T. | 2025-08-21 | — | — | US | claimed |
| EP-4599048-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-08-13 | — | — | EP | claimed |
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| EP-4549429-A1 | METHOD AND SYSTEM FOR THE PRODUCTION OF DISINFECTION AND/OR STERILISATION SOLUTIONS | Universitat Jaume I (ES) | 2025-05-07 | — | — | EP | claimed |
| CN-119764506-A | Negative electrode electrolyte of zinc-iron flow battery and zinc-iron flow battery | 中国石油大学(北京) | 2025-04-04 | — | — | CN | claimed |
| WO-2025071488-A1 | CAPACITY BOOSTERS FOR VANADIUM-BASED ELECTROLYTES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2025-04-03 | — | — | WO | claimed |
| CN-119654404-A | Methods and compositions for producing oligodendrocyte progenitor cells | 特雷尔赫德生物系统股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119425636-A | Molecularly imprinted composite core-shell adsorption material, preparation method and application | 南开大学 | 2025-02-14 | — | — | CN | claimed |
| EP-0091225-A2 | Anthraquinone compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-10-12 | — | — | EP | claimed |
| EP-0063490-A1 | Lactation improvement method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | claimed |
| US-4342701-A | Process for the preparation of 4,5-dinitro-1,8-dihydroxyanthraquinone | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-03 | — | — | US | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| EP-0000341-B1 | PROCESS FOR PREPARING PRACTICALLY PURE 1-AMINO-8-NITRO-4,5-DIHYDROXY ANTHRAQUINONE | BASF Aktiengesellschaft (DE) | 1981-02-25 | — | — | EP | claimed |
| EP-0015486-A2 | Process for the preparation of 4,5-dinitro-1,8-dihydroxyanthraquinone | BAYER AG (DE) | 1980-09-17 | — | — | EP | claimed |
| US-4154747-A | Production of virtually pure 1-amino-8-nitro-4,5-dihydroxyanthraquinone | BASF AKTIENGESELLSCHAFT (DE) | 1979-05-15 | — | — | US | claimed |
| EP-0000341-A1 | Process for preparing practically pure 1-amino-8-nitro-4,5-dihydroxy anthraquinone | BASF Aktiengesellschaft (DE) | 1979-01-24 | — | — | EP | claimed |
| US-4041164-A | ALUMINUM CHELATES OF A HYDROXY-QUINONE | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | claimed |
| US-4002654-A | Process for the preparation of dihydroxyanthraquinones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | claimed |