⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24387199 | 0.73 | — | — | |
| SCHEMBL4137728 | 0.71 | — | — | |
| SCHEMBL13520583 | 0.71 | — | — | |
| SCHEMBL16313059 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL18197628 | 0.69 | — | — | |
| SCHEMBL776681 | 0.69 | — | — | |
| SCHEMBL4137269 | 0.67 | — | — | |
| SCHEMBL21259887 | 0.65 | — | — | |
| SCHEMBL4047435 | 0.65 | — | — | |
| SCHEMBL5533547 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699179-A1 | PYRAZOLYL-CONTAINING TRICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) | 2020-08-26 | — | — | EP | disclosed |
| EP-2440569-B1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | ASTRAZENECA AB (SE) | 2016-08-24 | — | — | EP | disclosed |
| US-20150252077-A1 | Melanocortin Receptor-Specific Peptides | ASTRAZENECA AB (SE) | 2015-09-10 | — | — | US | disclosed |
| US-8455618-B2 | Melanocortin receptor-specific peptides | ASTRAZENECA AB (SE) | 2013-06-04 | — | — | US | disclosed |
| US-8455617-B2 | Melanocortin receptor-specific peptides | ASTRAZENECA AB (SE) | 2013-06-04 | — | — | US | disclosed |
| US-20120046219-A1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | ASTRAZENECA AB (SE) | 2012-02-23 | — | — | US | disclosed |
| US-20100311648-A1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDES | ASTRAZENECA AB (SE) | 2010-12-09 | — | — | US | disclosed |