⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137269 | 0.74 | — | — | |
| SCHEMBL14351626 | 0.70 | LMNA (0.30) | — | |
| SCHEMBL13520583 | 0.67 | — | — | |
| SCHEMBL4137728 | 0.67 | — | — | |
| SCHEMBL8368902 | 0.65 | — | — | |
| SCHEMBL776681 | 0.65 | — | — | |
| SCHEMBL5687715 | 0.61 | — | — | |
| SCHEMBL5984121 | 0.61 | — | — | |
| SCHEMBL18748 | 0.61 | — | — | |
| SCHEMBL21259887 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008000645-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |