Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928743 | 0.84 | GLA (0.41) | VDRALDH1A1GAAGLACYP3A4 | |
| SCHEMBL3935202 | 0.84 | GLA (0.41) | VDRALDH1A1GAAGLACYP3A4 | |
| SCHEMBL14779262 | 0.79 | GAA (0.46) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL1393862 | 0.78 | GAA (0.42) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL5468129 | 0.78 | GAA (0.42) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL25277145 | 0.78 | GAA (0.42) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL8309170 | 0.78 | GAA (0.42) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL5468126 | 0.78 | GAA (0.42) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL8345094 | 0.78 | GAA (0.45) | VDRALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL890842 | 0.78 | GAA (0.45) | VDRALDH1A1GAACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659735-B1 | PROCESS FOR PRODUCING ANILINE DERIVATIVE | SAGAMI CHEM RES (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5639915-A | Process for the production of aniline derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0659735-A1 | PROCESS FOR PRODUCING ANILINE DERIVATIVE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-28 | — | — | EP | disclosed |
| US-4355033-A | TREATMENT OF HYPERTENSION | HOFFMAN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4244957-A | HYPOTENSIVE AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |