Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468126 | 1.00 | GAA (0.42) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL1545381 | 0.86 | CA2 (0.47) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL1545434 | 0.86 | CA2 (0.47) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL1545377 | 0.86 | CA2 (0.47) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL16039239 | 0.83 | CA2 (0.42) | ALDH1A1CA2CA1MMP9MMP13 | |
| SCHEMBL14779262 | 0.83 | GAA (0.46) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL13105251 | 0.83 | ALDH1A1 (0.40) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL5551724 | 0.83 | PPARG (0.41) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL30661638 | 0.83 | CA2 (0.43) | GAAALDH1A1CA2CA1MMP1 | |
| SCHEMBL8345094 | 0.81 | GAA (0.45) | GAAALDH1A1CA2CA1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070026508-A1 | Enzymatic method of making 1,2-diol derivatives and their esters | ENZYTECH, LTD. (KR) | 2007-02-01 | — | — | US | disclosed |
| WO-2004097026-A1 | THE ENZYMATIC METHOD OF MAKING 1,2-DIOL DERIVATIVES AND THEIR ESTERS | ENZYTECH, LTD. (KR) | 2004-11-11 | — | — | WO | disclosed |
| EP-0759915-B1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS INC (US) | 2002-10-16 | — | — | EP | disclosed |
| WO-1999033468-A9 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS INC (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999033468-A1 | METHOD FOR TREATING HYPEROXIA | CELL THERAPEUTICS, INC. (US) | 1999-07-08 | — | — | WO | disclosed |
| EP-0759915-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031450-A1 | ASYMMETRIC SYNTHESIS OF CHIRAL SECONDARY ALCOHOLS | CELL THERAPEUTICS, INC. (US) | 1995-11-23 | — | — | WO | disclosed |