Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393149 | 0.84 | MAPT (0.62) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL10080086 | 0.80 | MAPT (0.77) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL16231160 | 0.80 | MAPT (0.50) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL5143251 | 0.75 | MAPT (0.51) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL13431190 | 0.72 | MAPT (0.49) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL5141777 | 0.70 | MAPT (0.51) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL7364265 | 0.69 | MAPT (0.74) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL13949416 | 0.67 | APEX1 (0.41) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL5146178 | 0.66 | MAPT (0.64) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL13033957 | 0.66 | MAPT (0.61) | MAPTTDP1LMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423396-B1 | SYNTHESIS OF TRIPHENYLPHOSPHONIUM QUINOLS AND QUINONES | ANTIPODEAN PHARMACEUTICALS INC (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2003016323-A1 | SYNTHESIS OF TRIPHENYLPHOSPHONIUM QUINOLS SND QUINONES | ANTIPODEAN BIOTECHNOLOGY LIMITED (NZ) | 2003-02-27 | — | — | WO | disclosed |