Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5143251 | 0.89 | MAPT (0.51) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL16231160 | 0.86 | MAPT (0.50) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL5141777 | 0.84 | MAPT (0.51) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL8368998 | 0.84 | MAPT (0.47) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL7364265 | 0.83 | MAPT (0.74) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL13431190 | 0.83 | MAPT (0.49) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL13033957 | 0.80 | MAPT (0.61) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL2458767 | 0.79 | MAPT (0.97) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL5146178 | 0.79 | MAPT (0.64) | MAPTTDP1LMNACYP3A4CYP2D6 | |
| SCHEMBL24783643 | 0.78 | IDO1 (0.56) | MAPTTDP1LMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4831265-A | ANTIFIBROTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | claimed |
| JP-58174343-A | — | — | None | — | — | JP | disclosed |
| US-20180022700-A1 | COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | BEIJING AN JIAN XI BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| EP-1423396-B1 | SYNTHESIS OF TRIPHENYLPHOSPHONIUM QUINOLS AND QUINONES | ANTIPODEAN PHARMACEUTICALS INC (US) | 2011-10-05 | — | — | EP | disclosed |
| US-20070260076-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | ZYMES, LLC | 2007-11-08 | — | — | US | disclosed |
| US-7179928-B2 | Synthesis of triphenylphosphonium quinols and quinones | ANTIPODEAN PHARMACEUTICALS, INC. (US) | 2007-02-20 | — | — | US | disclosed |
| US-4831265-A | ANTIFIBROTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| JP-S58174343-A | BENZOQUINONE DERIVATIVE | TAKEDA CHEM IND LTD | 1983-10-13 | — | — | JP | disclosed |
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022700-A1 | COMPOUND CONTAINING INDOLEACETIC ACID CORE STRUCTURE AND USE THEREOF | IDO1, TPH1, IDO2 | MAPT 3390/4885TDP1 4032/4885LMNA 2460/4885 |
| US-20070260076-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | SQOR, NDUFS6, NDUFS5 | MAPT 4024/4885TDP1 3402/4885LMNA 2961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.