Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | S100A4 | P26447 | 2/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051840 | 0.86 | TSHR (0.69) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28221727 | 0.86 | TDP1 (0.63) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL27930468 | 0.86 | TSHR (0.55) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3534700 | 0.84 | TSHR (0.53) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3191298 | 0.81 | TDP1 (0.53) | HSD17B10SMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL19608973 | 0.81 | HSD17B10 (0.62) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL15876114 | 0.80 | HSD17B10 (0.51) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6174336 | 0.80 | MAPK1 (0.52) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3537454 | 0.80 | TSHR (0.49) | HSD17B10TSHRSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL9444834 | 0.79 | TDP1 (0.71) | TSHRSMN1; SMN2TDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307772-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2021-08-27 | — | — | CN | disclosed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | disclosed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |