Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.66 |
| ▸ | FNTB | P49356 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369213 | 1.00 | FNTA (0.66) | FNTAFNTBALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL6056351 | 0.94 | FNTA (0.74) | FNTAFNTBCYP3A4 | |
| SCHEMBL6056346 | 0.94 | FNTA (0.74) | FNTAFNTBCYP3A4 | |
| SCHEMBL7624701 | 0.90 | FNTA (0.52) | FNTAFNTBALDH1A1 | |
| SCHEMBL7624707 | 0.90 | FNTA (0.52) | FNTAFNTBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8369181 | 0.86 | FNTA (0.66) | FNTAFNTBCYP3A4CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL8365955 | 0.86 | FNTA (0.66) | FNTAFNTBCYP3A4CYP2C19KMT2A | |
| SCHEMBL8329434 | 0.85 | FNTA (0.89) | FNTAFNTBCYP3A4CYP2C19 | |
| SCHEMBL8334563 | 0.85 | FNTA (0.89) | FNTAFNTBCYP3A4CYP2C19 | |
| SCHEMBL6056576 | 0.84 | FNTA (0.61) | FNTAFNTBCYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725650-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-02-03 | — | — | EP | claimed |
| EP-0725650-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1996-08-14 | — | — | EP | claimed |
| WO-1995009001-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1995-04-06 | — | — | WO | claimed |
| US-5576293-A | TETRAPEPTIDES, ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-19 | — | — | US | disclosed |