Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 14/20 | 0.81 |
| ▸ | SLC5A2 | P31639 | 10/20 | 0.81 |
| ▸ | SLC28A3 | Q9HAS3 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378176 | 0.94 | SLC5A1 (0.73) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL8378175 | 0.94 | SLC5A1 (0.73) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL8367167 | 0.90 | SLC5A1 (0.67) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL14104531 | 0.90 | SLC5A1 (1.00) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL6725644 | 0.90 | SLC5A1 (1.00) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL30268946 | 0.90 | SLC5A1 (1.00) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL7581216 | 0.90 | SLC5A1 (1.00) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL6724534 | 0.90 | SLC5A1 (0.66) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL13046266 | 0.90 | SLC5A1 (0.84) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL8380408 | 0.89 | SLC5A1 (0.66) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | claimed |
| US-5830873-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | claimed |
| JP-8193093-A | — | — | None | — | — | JP | disclosed |
| WO-2010138535-A1 | METHODS FOR TREATING TYPE 2 DIABETES IN PATIENTS RESISTANT TO PREVIOUS TREATMENT WITH OTHER ANTI-DIABETIC DRUGS EMPLOYING AN SGLT2 INHIBITOR AND COMPOSITIONS THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-12-02 | — | — | WO | disclosed |
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0773226-B1 | Propiophenone derivative and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5830873-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5767094-A | Propiophenone derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0773226-A1 | Propiophenone derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |
| JP-H08193093-A | PROPIOPHENONE DERIVATIVE AND ITS DERIVATIVE | TANABE SEIYAKU CO LTD | 1996-07-30 | — | — | JP | disclosed |
| EP-0684254-A1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |