Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 13/20 | 0.73 |
| ▸ | SLC5A2 | P31639 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378175 | 1.00 | SLC5A1 (0.73) | SLC5A1SLC5A2ALDH1A1SLC28A3HPGD | |
| SCHEMBL8369261 | 0.94 | SLC5A1 (0.81) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL8368371 | 0.88 | SLC5A1 (0.65) | SLC5A1SLC5A2ALDH1A1SLC28A3HPGD | |
| SCHEMBL8367167 | 0.88 | SLC5A1 (0.67) | SLC5A1SLC5A2ALDH1A1SLC28A3HPGD | |
| SCHEMBL8382096 | 0.85 | SLC5A1 (0.64) | SLC5A1SLC5A2ALDH1A1SLC28A3HPGD | |
| SCHEMBL8382094 | 0.85 | SLC5A1 (0.64) | SLC5A1SLC5A2ALDH1A1SLC28A3HPGD | |
| SCHEMBL8369287 | 0.85 | SLC5A1 (0.65) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL14104531 | 0.85 | SLC5A1 (1.00) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL6724534 | 0.85 | SLC5A1 (0.66) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 | |
| SCHEMBL6725644 | 0.85 | SLC5A1 (1.00) | SLC5A1SLC5A2SLC28A3HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| EP-0684254-A1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |