SCHEMBL8370581

SCHEMBL8370581

CNC(=O)/C(=N\OC)c1ccccc1COc1nc(OC)ccc1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.44
FLT4 P35916 2/20 0.35
PTK2 Q05397 1/20 0.35
MTNR1A P48039 2/20 0.34
MTNR1B P49286 2/20 0.34
SGMS2 Q8NHU3 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
POLB P06746 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370584 1.00 HIF1A (0.44) HIF1AFLT4PTK2MTNR1AMTNR1B
SCHEMBL8371571 0.93 HIF1A (0.44) HIF1AFLT4PTK2SGMS2MAOA
SCHEMBL8371570 0.93 HIF1A (0.44) HIF1AFLT4PTK2SGMS2MAOA
SCHEMBL8372656 0.91 HIF1A (0.42) HIF1AFLT4PTK2SGMS2MAOA
SCHEMBL8372658 0.91 HIF1A (0.42) HIF1AFLT4PTK2SGMS2MAOA
SCHEMBL8368455 0.89 HIF1A (0.44) HIF1APTK2SGMS2MAOAMAOB
SCHEMBL8368453 0.89 HIF1A (0.44) HIF1APTK2SGMS2MAOAMAOB
SCHEMBL8369594 0.87 HIF1A (0.42) HIF1AFLT4SGMS2MAOAMAOB
SCHEMBL8369593 0.87 HIF1A (0.42) HIF1AFLT4SGMS2MAOAMAOB
SCHEMBL8368450 0.87 HIF1A (0.43) HIF1APTK2SGMS2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617011-B1 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO (JP) 1999-01-20 EP disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed