SCHEMBL8369784

SCHEMBL8369784

CC(C)(c1ccccc1)c1cc(S(=O)(=O)O)c(O)c(C(C)(C)c2ccccc2)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.40
ESR2 Q92731 4/20 0.40
ALDH1A1 P00352 3/20 0.40
CYP3A4 P08684 1/20 0.40
PGAM1 P18669 1/20 0.38
NR3C2 P08235 3/20 0.36
CNR1 P21554 4/20 0.34
CNR2 P34972 4/20 0.34
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2D6 P10635 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MPL P40238 1/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8369084 0.88 ESR1 (0.38) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8368675 0.88 ALDH1A1 (0.38) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8367597 0.87 CNR1 (0.39) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8370466 0.87 CNR1 (0.39) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8369553 0.83 ESR2 (0.44) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8367502 0.83 ESR1 (0.44) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8367500 0.82 CYP3A4 (0.40) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8370475 0.81 PTPN1 (0.40) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8369552 0.80 ESR1 (0.43) ESR1ESR2ALDH1A1CYP3A4PGAM1
SCHEMBL8369674 0.80 TSHR (0.44) ESR1ESR2ALDH1A1CYP3A4NR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed