Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369927 | 0.96 | CYP1A2 (0.46) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL8370794 | 0.86 | KDM4E (0.50) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL8367465 | 0.84 | KDM4E (0.48) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL1030161 | 0.84 | KDM4E (0.48) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL6008963 | 0.82 | KDM4E (0.55) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL8371823 | 0.82 | KDM4E (0.55) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL8367682 | 0.82 | KDM4E (0.55) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL15532111 | 0.81 | KDM4E (0.53) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL8175230 | 0.81 | KDM4E (0.53) | CYP1A2KDM4EGMNNLMNAMAPT | |
| SCHEMBL8368995 | 0.81 | KDM4E (0.53) | CYP1A2KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999051619-A1 | ARABINOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-10-14 | — | — | WO | disclosed |