Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368086 | 0.92 | MAPT (0.61) | MAPTSMN1; SMN2TDP1POLBNPBWR1 | |
| SCHEMBL8369223 | 0.91 | MAPT (0.63) | MAPTSMN1; SMN2TDP1POLBNPBWR1 | |
| SCHEMBL8369096 | 0.91 | MAPT (0.58) | MAPTSMN1; SMN2TDP1POLBNPBWR1 | |
| Hydrochloric Acid SCHEMBL8370004 | 0.91 | MAPT (0.60) | MAPTSMN1; SMN2TDP1POLBNPBWR1 | |
| SCHEMBL8369156 | 0.82 | NPBWR1 (0.46) | MAPTSMN1; SMN2NPBWR1MEN1KMT2A | |
| SCHEMBL13425922 | 0.78 | MAPT (0.69) | MAPTSMN1; SMN2TDP1POLBMEN1 | |
| SCHEMBL8369155 | 0.77 | RPA1 (0.54) | NPBWR1MARS1ALDH1A1 | |
| SCHEMBL8366718 | 0.77 | SMN1; SMN2 (0.54) | MAPTSMN1; SMN2TDP1POLBMEN1 | |
| SCHEMBL8042554 | 0.77 | CNR2 (0.58) | MAPT | |
| Hydrochloric Acid SCHEMBL8369158 | 0.77 | RPA1 (0.53) | NPBWR1MARS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925768-A | ANTIINFLAMMATORY AGENTS; ANALGESICS, ANTICOAGULANTS, NARCOTICS | SANOFI (FR) | 1999-07-20 | — | — | US | disclosed |