Pyrogallol

Pyrogallol

SCHEMBL8370384

Nc1ccc(N)cc1.Oc1cccc(O)c1O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.71
ALOX15 P16050 5/20 0.71
TDP1 Q9NUW8 5/20 0.71
HSD17B10 Q99714 4/20 0.71
LMNA P02545 3/20 0.71
HPGD P15428 3/20 0.71
CA2 P00918 3/20 0.71
CA6 P23280 2/20 0.71
EGFR P00533 2/20 0.71
FYN P06241 2/20 0.71
MMP9 P14780 2/20 0.71
RECQL P46063 2/20 0.71
CA1 P00915 2/20 0.71
ADAMTS4 O75173 1/20 0.71
MMP2 P08253 1/20 0.71
MMP8 P22894 1/20 0.71
CDK2 P24941 1/20 0.71
MMP12 P39900 1/20 0.71
ADAMTS5 Q9UNA0 1/20 0.71
CYP3A4 P08684 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrogallol SCHEMBL3532 0.84
Pyrogallol SCHEMBL170157 0.84 ALDH1A1 (1.00) ALDH1A1ALOX15TDP1HSD17B10LMNA
Aminobenzoic Acid SCHEMBL28309126 0.82 CA1 (0.48) ALDH1A1ALOX15TDP1HSD17B10LMNA
Pyrogallol SCHEMBL27674772 0.81 ALDH1A1 (0.80) ALDH1A1ALOX15TDP1HSD17B10LMNA
Catechol SCHEMBL4691187 0.81 CYP3A4 (0.67) ALDH1A1ALOX15TDP1HSD17B10LMNA
Pyrogallol SCHEMBL442053 0.81 ALDH1A1 (0.92) ALDH1A1ALOX15TDP1HSD17B10LMNA
Pyrogallol SCHEMBL4884788 0.81 ALDH1A1 (0.92) ALDH1A1ALOX15TDP1HSD17B10LMNA
Pyrogallol SCHEMBL1042997 0.81 ALDH1A1 (0.92) ALDH1A1ALOX15TDP1HSD17B10LMNA
Pyrogallol SCHEMBL11324823 0.81 ALDH1A1 (0.92) ALDH1A1ALOX15TDP1HSD17B10LMNA
Pyrogallol SCHEMBL6270291 0.81 ALDH1A1 (0.92) ALDH1A1ALOX15TDP1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5889103-A CONSISTS OF A POLYMER OF QUINONE OR DERIVATIVES, A WATER SOLUBLE POLYMER, AN INORGANIC COLLOID AND AN ALKALI METAL SILICATE; USED AS ANTISCALING AGENT IN POLYMERIZATION OF ETHYLENICALLY UNSATURATED MONOMERS IN ALKALINE SOLUTION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-30 US disclosed
EP-0760378-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1999-01-27 EP disclosed
US-5728781-A POLYMERIZING AN UNSATURATED MONOMER IN A VESSEL HAVING A COATING FILM ON THE INNER WALL SURFACE THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-17 US disclosed
EP-0632058-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-01-28 EP disclosed
US-5691428-A Process for producing a polymer using a quinone compound condensation product polymer scale preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-11-25 US disclosed
EP-0760378-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0540934-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1997-02-05 EP disclosed
EP-0534434-B1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHINETSU CHEMICAL CO (JP) 1996-12-11 EP disclosed
US-5457170-A Coating interior wall of vessel used for addition polymerization SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-10-10 US disclosed
US-5442017-A Addition polymerization in vessel with interior wall coating comprised of condesation product of aromatic amine, aromatic alcohol and acetone plus polymeric material and colloidal silica SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-08-15 US disclosed
US-5424003-A Preventive coatings for equipment and reactors used for addition polymerization of unsaturated compounds; antideposit agents; amino resins SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-06-13 US disclosed
US-5399613-A Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-03-21 US disclosed
EP-0632058-A1 Polymer scale preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-01-04 EP disclosed
EP-0540934-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-05-12 EP disclosed
EP-0534434-A1 Polymer scale preventive agent, polymerization vessel effective in preventing polymer scale deposition, and process of producing polymer using said vessel Shin-Etsu Chemical Co., Ltd. (JP) 1993-03-31 EP disclosed
US-4297098-A COLOR DEVELOPMENT BY ATMOSPHERIC OXYDATION OF A MIXTURE OF P-PHENYLENEDIAMINE OR 2,4-DIAMINOTOLUENE, PYROGALLOL, AND M-AMINOPHENOL ALBERTO-CULVER COMPANY (US) 1981-10-27 US disclosed