SCHEMBL8370437

SCHEMBL8370437

CC(CC(c1ccccc1)c1cc(Cc2ccccc2)cc(S(=O)(=O)O)c1O)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.37
PTPN1 P18031 3/20 0.34
PTPN2 P17706 1/20 0.34
PTPN6 P29350 1/20 0.34
PGAM1 P18669 1/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
CASR P41180 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
ELANE P08246 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370514 0.85 TRPA1 (0.40) TRPA1PGAM1CYP1A2CYP2C9CYP3A4
SCHEMBL8365840 0.85 TYR (0.39) PTPN1PTPN2PTPN6PGAM1CYP1A2
SCHEMBL8368667 0.84 FABP3 (0.41) TRPA1PGAM1CYP1A2CYP2C9CYP3A4
SCHEMBL8367645 0.83 TRPV1 (0.40) LMNAKMT2AHPGDNPSR1
SCHEMBL8370521 0.83 TRPV1 (0.40) LMNAKMT2AHPGDNPSR1
SCHEMBL8365850 0.83 TRPA1 (0.38) TRPA1PGAM1CYP1A2CYP2C9CYP3A4
SCHEMBL8367569 0.83 TRPA1 (0.38) TRPA1PGAM1CYP1A2CYP2C9CYP3A4
SCHEMBL8367612 0.83 TYR (0.38) PTPN1PTPN2PTPN6PGAM1CYP1A2
SCHEMBL8369544 0.82 CYP1A2 (0.51) TRPA1PGAM1CYP1A2CYP2C9CYP3A4
SCHEMBL8368243 0.81 TRPA1 (0.39) TRPA1PGAM1CYP1A2CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed