SCHEMBL837048

SCHEMBL837048

N#CCc1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6848665 0.77
SCHEMBL3228483 0.76
SCHEMBL348694 0.76
SCHEMBL1306440 0.76
SCHEMBL6545428 0.76
SCHEMBL31338920 0.73 MEN1 (0.46)
SCHEMBL29058846 0.73
SCHEMBL10768701 0.73
SCHEMBL10987832 0.72
SCHEMBL24859001 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469741-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2016-10-18 US claimed
EP-2203482-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORP (JP) 2015-11-25 EP claimed
CN-104945540-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2015-09-30 CN claimed
US-20150267031-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2015-09-24 US claimed
US-9085646-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2015-07-21 US claimed
WO-2014141110-A2 AMINONITRILES AS KYNURENINE PATHWAY INHIBITORS CURADEV PHARMA PVT. LTD. (IN) 2014-09-18 WO claimed
US-20130066016-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-14 US claimed
US-8362156-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2013-01-29 US claimed
US-8314189-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2012-11-20 US claimed
US-20100280217-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-11-04 US claimed
CN-101874044-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2010-10-27 CN claimed
EP-2203482-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS Bridgestone Corporation (JP) 2010-07-07 EP claimed
EP-1901750-B1 TUMOR TREATMENT WITH GLIOTOXIN DERIVATIVES UNIV WIEN MED (AT) 2010-02-24 EP claimed
WO-2009051702-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-04-23 WO claimed
WO-2009051700-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (US) 2009-04-23 WO claimed
US-20090099325-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION 2009-04-16 US claimed
US-20080064876-A1 Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione CELGENE CORPORATION 2008-03-13 US claimed
WO-2007136640-A2 PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE CELGENE CORPORATION (US) 2007-11-29 WO claimed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US claimed
WO-2026102105-A1 FUNCTIONAL POLYBUTADIENE AND CARBON BLACK IN RUBBER COMPOUNDS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2026-05-15 WO disclosed
CN-119118967-A Preparation method of 2-furanone acid 重庆新征程生物医药有限公司 2024-12-13 CN disclosed
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed
WO-2023196527-A2 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 WO disclosed
CN-116514799-A Wee1 inhibitor, composition and application thereof 星希尔生物科技(上海)有限公司 2023-08-01 CN disclosed
CN-113004252-B Aryl imidazole derivative and application thereof 江苏先声药业有限公司 2023-06-09 CN disclosed
CN-113347880-B Safety compositions comprising a pyridine carboxylate herbicide and a bisbenzoxazole acid 科迪华农业科技有限责任公司 2023-02-17 CN disclosed
CN-115490616-A Compound containing cyano-substituted p-phenylene ethylene structure, luminescent crystal and optical application thereof 山东海化集团有限公司 2022-12-20 CN disclosed
US-11512148-B2 Composition including multiple terminally functionalized polymers BRIDGESTONE CORPORATION (JP) 2022-11-29 US disclosed
US-20220153885-A1 PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2022-05-19 US disclosed
CN-114451413-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in vegetables 美国陶氏益农公司 2022-05-10 CN disclosed
CN-114451412-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi 美国陶氏益农公司 2022-05-10 CN disclosed
CN-114223661-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in row crops 美国陶氏益农公司 2022-03-25 CN disclosed
CN-114057633-A Process for preparing 4-alkoxy-3-hydroxypicolinic acids 美国陶氏益农公司 2022-02-18 CN disclosed
CN-111182791-B Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in vegetables 美国陶氏益农公司 2021-12-21 CN disclosed
CN-111132550-B Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in row crops 美国陶氏益农公司 2021-12-21 CN disclosed
CN-113767107-A Process for producing crystalline L-glufosinate ammonium salt monohydrate 巴斯夫欧洲公司 2021-12-07 CN disclosed
CN-110933931-B Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in orchards, vineyards and plantation crops 美国陶氏益农公司 2021-10-26 CN disclosed
CN-110996665-B Use of acyclic picolinamides as fungicides against fungal diseases on turfgrass 陶氏益农公司 2021-10-26 CN disclosed
CN-113453551-A Compositions comprising a pyridine carboxylate herbicide and an azole carboxylate safener 科迪华农业科技有限责任公司 2021-09-28 CN disclosed
CN-113453550-A Safe compositions comprising a pyridine carboxylate herbicide and quinoxyacetic acid 科迪华农业科技有限责任公司 2021-09-28 CN disclosed
CN-113395900-A Compositions comprising a carboxypyridine herbicide and a 4-hydroxyphenyl-pyruvate dioxygenase (HPPD) inhibitor herbicide 科迪华农业科技有限责任公司 2021-09-14 CN disclosed
CN-113365499-A Compositions comprising a carboxylate pyridine herbicide and a fatty acid and lipid synthesis inhibitor herbicide 科迪华农业科技有限责任公司 2021-09-07 CN disclosed
CN-113347880-A Safe compositions comprising a pyridine carboxylate herbicide and a bisbenzoxazole acid 科迪华农业科技有限责任公司 2021-09-03 CN disclosed
CN-113329627-A Compositions comprising a carboxypyridine herbicide and an acetyl-CoA carboxylase (ACCASE) inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-31 CN disclosed
CN-113329628-A Compositions comprising a picolinate ester herbicide and a Very Long Chain Fatty Acid (VLCFA) synthesis inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-31 CN disclosed
CN-113271778-A Compositions comprising a carboxypyridine herbicide and a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-17 CN disclosed
CN-113226036-A Compositions comprising a pyridine carboxylate herbicide and a microtubule assembly inhibitor herbicide 科迪华农业科技有限责任公司 2021-08-06 CN disclosed
CN-113226033-A Compositions comprising chlorofluoropyridinates safe for white clover and methods of use thereof 科迪华农业科技有限责任公司 2021-08-06 CN disclosed
CN-113056195-A Compositions comprising picolinate ester herbicides and acetolactate synthase (ALS) inhibitor herbicides 科迪华农业科技有限责任公司 2021-06-29 CN disclosed
CN-113056196-A Compositions comprising picolinate ester herbicides and glyphosate or glufosinate 科迪华农业科技有限责任公司 2021-06-29 CN disclosed
CN-113004252-A Aryl imidazole derivative and application thereof 江苏先声药业有限公司 2021-06-22 CN disclosed
CN-112996393-A Compositions comprising a pyridine carboxylate herbicide and a synthetic auxin herbicide or an auxin transport inhibitor 科迪华农业科技有限责任公司 2021-06-18 CN disclosed
CN-112969370-A Compositions comprising a carboxypyridine herbicide and a PDS inhibitor herbicide 科迪华农业科技有限责任公司 2021-06-15 CN disclosed
CN-112955011-A Compositions comprising a carboxypyridine herbicide in combination with a photosystem II and optionally an HPPD inhibitor herbicide 科迪华农业科技有限责任公司 2021-06-11 CN disclosed
CN-112955012-A Compositions comprising a pyridine carboxylate herbicide and a plant growth regulator 科迪华农业科技有限责任公司 2021-06-11 CN disclosed
CN-109415457-B Method for preparing functionalized polymers 株式会社普利司通 2021-05-25 CN disclosed
CN-112739822-A Method for improving L-glufosinate-ammonium yield 巴斯夫欧洲公司 2021-04-30 CN disclosed
EP-3458488-B1 PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORP (JP) 2020-12-30 EP disclosed
US-20200369791-A1 Composition Including Multiple Terminally Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2020-11-26 US disclosed
EP-3732210-A1 COMPOSITION INCLUDING MULTIPLE TERMINALLY FUNCTIONALIZED POLYMERS Bridgestone Corporation (JP) 2020-11-04 EP disclosed
CN-106573005-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2020-05-29 CN disclosed
CN-111182791-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in vegetables 美国陶氏益农公司 2020-05-19 CN disclosed
CN-111132550-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in row crops 美国陶氏益农公司 2020-05-08 CN disclosed
CN-106659724-B Process for preparing 4-alkoxy-3-hydroxypicolinic acid 美国陶氏益农公司 2020-04-28 CN disclosed
CN-110996665-A Use of acyclic picolinamides as fungicides against fungal diseases on turfgrass 陶氏益农公司 2020-04-10 CN disclosed
CN-110933931-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in orchards, vineyards and plantation crops 美国陶氏益农公司 2020-03-27 CN disclosed
US-10550203-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2020-02-04 US disclosed
US-10370460-B1 Process for producing functionalized polymers BRIDGESTONE CORPORATION (JP) 2019-08-06 US disclosed
US-20190185598-A1 Process For Producing Functionalized Polymers BRIDGESTONE CORPORATION (JP) 2019-06-20 US disclosed
EP-3458488-A1 PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS Bridgestone Corporation (JP) 2019-03-27 EP disclosed
US-20180319905-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-11-08 US disclosed
WO-2017201397-A1 PROCESS FOR PRODUCING FUNCTIONALIZED POLYMERS BRIDGESTONE CORPORATION (JP) 2017-11-23 WO disclosed
EP-3029074-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORP (JP) 2017-08-02 EP disclosed
US-20170015760-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2017-01-19 US disclosed
US-9469741-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2016-10-18 US disclosed
EP-2647697-B1 METHOD FOR PRODUCING HEMATOPOIETIC STEM CELLS USING PYRAZOLE COMPOUND NISSAN CHEMICAL IND LTD (JP) 2016-08-24 EP disclosed
EP-3029074-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS Bridgestone Corporation (JP) 2016-06-08 EP disclosed
US-9290537-B2 Method for cross-linking peptides UNIVERSITEIT GENT (BE) 2016-03-22 US disclosed
US-9290537-B2 Method for cross-linking peptides UNIVERSITEIT GENT (BE) 2016-03-22 US disclosed
CN-105324369-A Tetrahydrofuran derivatives and use thereof as plasticizers BASF SE 2016-02-10 CN disclosed
US-9212348-B2 Method for producing hematopoietic stem cells using pyrazole compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-12-15 US disclosed
EP-2203482-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORP (JP) 2015-11-25 EP disclosed
CN-104945540-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2015-09-30 CN disclosed
US-20150267031-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2015-09-24 US disclosed
US-9085646-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2015-07-21 US disclosed
EP-2647629-B1 PYRAZOLE COMPOUNDS HAVING THERAPEUTIC EFFECT ON MULTIPLE MYELOMA NISSAN CHEMICAL IND LTD (JP) 2015-06-17 EP disclosed
US-20140057353-A1 METHOD FOR PRODUCING HEMATOPOIETIC STEM CELLS USING PYRAZOLE COMPOUNDS REPROCELL INCORPORATED (JP) 2014-02-27 US disclosed
US-8658686-B2 Pyrazole compounds having therapeutic effect on multiple myeloma NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-02-25 US disclosed
US-20130289239-A1 METHOD FOR CROSS-LINKING PEPTIDES UNIVERSITEIT GENT (BE) 2013-10-31 US disclosed
US-20130289239-A1 METHOD FOR CROSS-LINKING PEPTIDES UNIVERSITEIT GENT (BE) 2013-10-31 US disclosed
EP-2647629-A1 PYRAZOLE COMPOUND HAVING THERAPEUTIC EFFECT ON MULTIPLE MYELOMA Nissan Chemical Industries, Ltd. (JP) 2013-10-09 EP disclosed
EP-2647697-A1 METHOD FOR PRODUCING HEMATOPOIETIC STEM CELLS USING PYRAZOLE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2013-10-09 EP disclosed
US-20130253204-A1 PYRAZOLE COMPOUNDS HAVING THERAPEUTIC EFFECT ON MULTIPLE MYELOMA NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-26 US disclosed
CN-103237793-A Pyrazole compound having therapeutic effect on multiple myeloma NISSAN CHEMICAL IND LTD 2013-08-07 CN disclosed
US-20130066016-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-14 US disclosed
US-8362156-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2013-01-29 US disclosed
US-8314189-B2 Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORPORATION (JP) 2012-11-20 US disclosed
US-8142936-B2 Non-aqueous electrolyte and lithium secondary battery using the same LG CHEM, LTD. (KR) 2012-03-27 US disclosed
US-8142936-B2 Non-aqueous electrolyte and lithium secondary battery using the same LG CHEM, LTD. (KR) 2012-03-27 US disclosed
US-20100280217-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2010-11-04 US disclosed
CN-101874044-A Polymers functionalized with heterocyclic nitrile compounds BRIDGESTONE CORP 2010-10-27 CN disclosed
US-7767696-B2 Antitumor agents; tyrosine inhbitor; controllling kinase signal transduction MERCK PATENT GMBH (DE) 2010-08-03 US disclosed
EP-2203482-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS Bridgestone Corporation (JP) 2010-07-07 EP disclosed
US-20090131437-A1 DISUBSTITUTED UREAS AS KINASE INHIBITORS CORIUM INTERNATIONAL, INC. (US) 2009-05-21 US disclosed
WO-2009051700-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (US) 2009-04-23 WO disclosed
WO-2009051702-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2009-04-23 WO disclosed
US-20090099325-A1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS BRIDGESTONE CORPORATION 2009-04-16 US disclosed
US-20080207699-A1 Pyrazole Derivatives MERCK PATENT GMBH (DE) 2008-08-28 US disclosed
US-20080064876-A1 Process for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione CELGENE CORPORATION 2008-03-13 US disclosed
WO-2007136640-A2 PROCESSES FOR THE PREPARATION OF SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)ISOINDOLE-1,3-DIONE CELGENE CORPORATION (US) 2007-11-29 WO disclosed
WO-2007117180-A1 AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) 2007-10-18 WO disclosed
EP-1838700-A2 DISUBSTITUTED UREAS AS KINASE INHIBITORS Novartis AG (CH) 2007-10-03 EP disclosed
US-20070141475-A1 Non-aqueous electrolyte and lithium secondary battery using the same LG ENERGY SOLUTION, LTD. (KR) 2007-06-21 US disclosed
US-20070141475-A1 Non-aqueous electrolyte and lithium secondary battery using the same LG ENERGY SOLUTION, LTD. (KR) 2007-06-21 US disclosed
EP-0823908-B1 PYRIDO[2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION WARNER LAMBERT CO (US) 2006-11-02 EP disclosed
WO-2006072589-A2 DISUBSTITUTED UREAS AS KINASE INHIBITORS NOVARTIS AG (CH) 2006-07-13 WO disclosed
EP-1204671-B1 FLUOROGENIC COMPOUNDS AND USES THEREFOR 3M INNOVATIVE PROPERTIES CO (US) 2003-12-03 EP disclosed
EP-1090923-B1 Process for the preparation of ruthenium hydrogenation catalysts and use thereof DU PONT (US) 2003-07-16 EP disclosed
US-6566508-B2 Compound for use in the accurate detection of food parasites 3M INNOVATIVE PROPERTIES COMPANY 2003-05-20 US disclosed
EP-1090905-B1 Use of ruthenium hydrogenation catalysts DU PONT (US) 2002-12-18 EP disclosed
EP-1031379-B1 Catalyst comprising rutheniumcomplex, and use thereof in hydrogenation of unsaturated substrates, especially organic nitriles DU PONT (US) 2002-10-23 EP disclosed
US-20020147317-A1 Fluorogenic compounds and uses therefor 3M INNOVATIVE PROPETIES COMPANY 2002-10-10 US disclosed
EP-1204671-A1 FLUOROGENIC COMPOUNDS AND USES THEREFOR 3M Innovative Properties Company (US) 2002-05-15 EP disclosed
US-6372895-B1 USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY 3M INNOVATIVE PROPERTIES COMPANY 2002-04-16 US disclosed
EP-0839150-B1 PROCESS FOR THE PREPARATION OF RUTHENIUM HYDROGENATION CATALYSTS AND PRODUCTS THEREOF DU PONT (US) 2001-12-05 EP disclosed
EP-1155011-A1 DI- AND TRIPEPTIDE NITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND CATHEPSIN S AstraZeneca AB (SE) 2001-11-21 EP disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed
EP-0807119-B1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES AND THEIR IN SITU USE AS HYDROGENATION CATALYSTS DU PONT (US) 2001-07-18 EP disclosed
EP-1090905-A1 Process for the preparation of ruthenium hydrogenation catalysts and products thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-04-11 EP disclosed
EP-1090923-A1 Process for the preparation of ruthenium hydrogenation catalysts and products thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-04-11 EP disclosed
US-6215016-B1 HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA TORAY INDUSTRIES, INC. (JP) 2001-04-10 US disclosed
WO-2001010881-A1 FLUOROGENIC COMPOUNDS AND USES THEREFOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-02-15 WO disclosed
EP-1031379-A1 Catalyst comprising rutheniumcomplex, and use thereof in hydrogenation of unsaturated substrates, especially organic nitriles E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-08-30 EP disclosed
WO-2000049008-A1 DI- AND TRIPEPTIDE NITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND CATHEPSIN S ASTRAZENECA AB (SE) 2000-08-24 WO disclosed
EP-0807120-B1 RUTHENIUM HYDROGENATION CATALYSTS DU PONT (US) 2000-04-26 EP disclosed
CN-1046713-C Tetrahydroisoquinoline compounds, pharmaceutical compositions containing them, and their preparation and use KNORR CO LTD (GB) 1999-11-24 CN disclosed
US-5945422-A ANTICANCER AGENTS; ATHEROSCLEROSIS; RESTENOSIS; PSORIASIS WARNER-LAMBERT COMPANY (US) 1999-08-31 US disclosed
US-5807868-A ANALGESICS; PSYCHOLOGICAL DISORDES; PARKINSON*S DIESASE;COGNITION ACTIVATORS; DRUG DEPENDENCE; DYSKINESIA KNOLL AKTIENGESELLSCHAFT (DE) 1998-09-15 US disclosed
EP-0807098-B1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES DU PONT (US) 1998-09-09 EP disclosed
US-5804586-A ANALGESICS, PSYCHOLOGICAL DISORDERS KNOLL AKTIENGESELLSCHAFT (DE) 1998-09-08 US disclosed
US-5763669-A CONTACTING NITRILE WITH GASEOUS HYDROGEN IN PRESENCE OF ORGANORUTHENIUM CATALYST CONTAINING ORGANOPHOSPHORUS LIGAND, AGITATING THE NITRILE, HYDROGEN AND CATALYST TO FORM PRIMARY AMINE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-09 US disclosed
EP-0841063-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1998-05-13 EP disclosed
EP-0707570-B1 ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS KNOLL AG (DE) 1998-05-06 EP disclosed
EP-0839150-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM HYDROGENATION CATALYSTS AND PRODUCTS THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-05-06 EP disclosed
US-5741955-A TRANSITION METAL COMPLEX CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-21 US disclosed
US-5733914-A Pyrido 2, 3-d!pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation WARNER-LAMBERT COMPANY (US) 1998-03-31 US disclosed
US-5726334-A HYDROGENATION OF NITRILES TO PRIMARY AMINES; REDUCTIVE HYDROLYSIS OF NITRILES TO ALCOHOLS AND HYDROXYNITRILES; HYDROGENATION OF NITRO COMPOUNDS TO PRIMARY AMINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-10 US disclosed
EP-0823908-A1 PYRIDO 2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 1998-02-18 EP disclosed
EP-0807098-A1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-19 EP disclosed
EP-0807119-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES AND THEIR IN SITU USE AS HYDROGENATION CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-19 EP disclosed
EP-0807120-A1 RUTHENIUM HYDROGENATION CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-19 EP disclosed
US-5689003-A CATALYTIC HYDROGENATION OF NITRILES TO FORM AMINES WITH COMPLEXES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-18 US disclosed
US-5620981-A ANTICARCINOGENIC AGENTS, ATHEROSCLEROSIS, RESTENOSIS, PSORIASIS WARNER-LAMBERT COMPANY (US) 1997-04-15 US disclosed
US-5599962-A FOR HYDROGENATING ORGANIC NITRILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-04 US disclosed
WO-1996034867-A1 PYRIDO[2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION WARNER-LAMBERT COMPANY (US) 1996-11-07 WO disclosed
US-5559262-A PHOSPHINE LIGANDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-24 US disclosed
US-5554778-A IMINATION, REDUCTIVE HYDROLYSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-10 US disclosed
CN-1128992-A Therapeutic agents KNORR CO LTD (DE) 1996-08-14 CN disclosed
WO-1996023802-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM HYDROGENATION CATALYSTS AND PRODUCTS THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-08 WO disclosed
WO-1996023804-A1 PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES AND THEIR IN SITU USE AS HYDROGENATION CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-08 WO disclosed
WO-1996023753-A1 IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-08 WO disclosed
WO-1996023803-A1 RUTHENIUM HYDROGENATION CATALYSTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-08 WO disclosed
EP-0707570-A1 ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS Knoll AG (DE) 1996-04-24 EP disclosed
WO-1995000489-A1 ISOQUINOLINE DERIVATIVES AS THERAPEUTIC AGENTS KNOLL AG (DE) 1995-01-05 WO disclosed
EP-0355612-B1 Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1994-07-27 EP disclosed
US-5308857-A Antiulcer agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-03 US disclosed
CN-1040796-A The preparation method of fruylthiazole derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1990-03-28 CN disclosed
EP-0355612-A2 Furylthiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-02-28 EP disclosed
US-4656233-A \"Living\" polymers and chain transfer-regulated polymerization process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US disclosed
EP-0186330-A1 \"Living\" polymers and chain transfer-regulated polymerization process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-02 EP disclosed
US-4588484-A Electrochemical reduction of 3-chlorobenzo[b]thiophenes ELI LILLY AND COMPANY (US) 1986-05-13 US disclosed
US-4378314-A FOR PENICILLINS AND CEPHALOSPORINS BRISTOL MYERS COMPANY (US) 1983-03-29 US disclosed
US-4272437-A PENICILLINS BRISTOL-MYERS COMPANY (US) 1981-06-09 US disclosed
US-4254059-A TO PRIMARY AMINES UNDER MILD CONDITIONS USING A GROUP 8 METAL ANIONIC CATALYST COMPOSITION ALLIED CHEMICAL CORPORATION (US) 1981-03-03 US disclosed
US-4187314-A DOPAMINERGIC ACTIVITY SMITHKLINE CORPORATION (US) 1980-02-05 US disclosed
US-4111957-A DOPAMINERGIC SMITHKLINE CORPORATION (US) 1978-09-05 US disclosed
US-4107178-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1978-08-15 US disclosed
US-4086420-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-04-25 US disclosed
US-4051151-A Thiophene derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-09-27 US disclosed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US disclosed
US-4046814-A Preparation of diketones WRIGHT STATE UNIVERSITY (US) 1977-09-06 US disclosed