⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804490 | 0.78 | — | — | |
| SCHEMBL327550 | 0.78 | — | — | |
| SCHEMBL8146532 | 0.78 | ALDH1A1 (0.54) | — | |
| SCHEMBL837048 | 0.77 | — | — | |
| SCHEMBL6745896 | 0.75 | CHRM2 (0.61) | — | |
| SCHEMBL11199896 | 0.75 | ALDH1A1 (0.49) | — | |
| SCHEMBL7094868 | 0.74 | ALDH1A1 (0.67) | — | |
| SCHEMBL11060991 | 0.74 | ALDH1A1 (0.61) | — | |
| SCHEMBL10543352 | 0.72 | ALDH1A1 (0.47) | — | |
| SCHEMBL18884496 | 0.72 | PDE4A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8213168-A | — | — | None | — | — | JP | disclosed |
| EP-0861843-B1 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | TERUMO CARDIOVASCULAR SYS (US) | 2004-07-14 | — | — | EP | disclosed |
| US-5958782-A | FLUORESCENT IONOPHORIC COMPOUND IS DISCLOSED THAT INCLUDES A COMPLEXING MOIETY, SUCH AS A CRYPTAND OR CROWN-ETHER PORTION, AND A FLUORESCING MOIETY SUCH AS A COUMARIN PORTION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0861843-A2 | Fluorescent ionophoric compounds with a cryptand/crown-ether portion and a coumarin portion, their preparation and their use for measuring metal cation concentrations | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | disclosed |
| JP-H08213168-A | MANUFACTURE OF ELECTROLUMINESCENT ELEMENT | ALPS ELECTRIC CO LTD | 1996-08-20 | — | — | JP | disclosed |
| EP-0500653-A4 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0500653-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991006548-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST, INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| US-5008270-A | 2-amino-7-(heterocyclomethyl)-3H,5H-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same | BIOCRYST, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |