SCHEMBL8370501

SCHEMBL8370501

CNC(=O)/C(=N\OC)c1ccccc1Oc1cccc(O)c1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.53
RAB9A P51151 2/20 0.41
POLB P06746 2/20 0.41
NPC1 O15118 1/20 0.41
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP3A4 P08684 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MTNR1B P49286 1/20 0.37
CTNNB1 P35222 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954664 1.00 HIF1A (0.53) HIF1ARAB9APOLBNPC1KDM4E
SCHEMBL8370502 1.00 HIF1A (0.53) HIF1ARAB9APOLBNPC1KDM4E
SCHEMBL8368475 0.89 POLB (0.50) HIF1ARAB9APOLBNPC1KDM4E
SCHEMBL8370504 0.89 RAB9A (0.44) HIF1ARAB9APOLBKDM4EMEN1
SCHEMBL8954792 0.89 RAB9A (0.44) HIF1ARAB9APOLBKDM4EMEN1
SCHEMBL8368474 0.89 POLB (0.50) HIF1ARAB9APOLBNPC1KDM4E
SCHEMBL8370505 0.89 RAB9A (0.44) HIF1ARAB9APOLBKDM4EMEN1
SCHEMBL8371669 0.88 KDM4E (0.49) HIF1ARAB9APOLBNPC1KDM4E
SCHEMBL8371654 0.88 GAA (0.44) HIF1ARAB9APOLBNPC1KDM4E
SCHEMBL8954629 0.88 GAA (0.44) HIF1ARAB9APOLBNPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617011-B1 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO (JP) 1999-01-20 EP disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed