SCHEMBL8370528

SCHEMBL8370528

Cc1ccc(S(=O)(=O)O)c(O)c1C(CC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.40
LMNA P02545 2/20 0.37
CYP2C9 P11712 4/20 0.36
VKORC1 Q9BQB6 1/20 0.36
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ELANE P08246 1/20 0.33
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.33
GRIA4 P48058 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8367573 0.88 TRPA1 (0.41) TRPA1LMNACYP2C9VKORC1CYP1A2
SCHEMBL8367496 0.86 TRPA1 (0.42) TRPA1LMNACYP2C9VKORC1GRIA4
SCHEMBL8365817 0.82 VKORC1 (0.40) LMNAVKORC1ATML3MBTL1ELANE
SCHEMBL8370422 0.82 TRPA1 (0.40) TRPA1LMNACYP2C9VKORC1ATM
SCHEMBL8370499 0.81 TRPA1 (0.38) TRPA1LMNACYP2C9VKORC1ATM
SCHEMBL8368243 0.81 TRPA1 (0.39) TRPA1LMNACYP2C9VKORC1CYP1A2
SCHEMBL8368895 0.80 VKORC1 (0.39) LMNAVKORC1ATML3MBTL1ELANE
SCHEMBL8365997 0.79 TRPA1 (0.38) TRPA1LMNACYP2C9VKORC1CYP1A2
SCHEMBL8367498 0.77 TRPA1 (0.41) TRPA1LMNACYP2C9ELANECYP1A2
SCHEMBL8368404 0.77 TRPA1 (0.38) TRPA1LMNACYP2C9VKORC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714785-B1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI CHEMICALS INC (JP) 1999-01-07 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed