Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | S100A9 | P06702 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558316 | 0.90 | KMT2A (0.49) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL294676 | 0.87 | PNMT (0.54) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL29581044 | 0.87 | PNMT (0.54) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL14426942 | 0.85 | KMT2A (0.52) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL294675 | 0.85 | PNMT (0.52) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL28332854 | 0.85 | PNMT (0.52) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL30502958 | 0.85 | PNMT (0.52) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL2343233 | 0.85 | PNMT (0.52) | PNMTKMT2ARXFP1TAAR1CYP3A4 | |
| SCHEMBL2377120 | 0.83 | PNMT (0.50) | PNMTTAAR1CYP3A4IDO1AGXT | |
| SCHEMBL2377117 | 0.83 | PNMT (0.50) | PNMTKMT2ARXFP1TAAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765339-B1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES CONTAINING AN ARGININE MIMIC AS ENZYME INHIBITORS | CORVAS INT INC (US) | 1999-01-27 | — | — | EP | disclosed |