Naphthalene

Naphthalene

SCHEMBL8370634

NN1CCC[C@H]1C(=O)O.c1ccc2ccccc2c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP1A2 P05177 1/20 0.48
ITGB3 P05106 1/20 0.43
ITGB1 P05556 1/20 0.43
ITGAV P06756 1/20 0.43
ITGA5 P08648 1/20 0.43
ITGA4 P13612 1/20 0.43
KMT2A Q03164 3/20 0.42
THRB P10828 1/20 0.42
ALOX12 P18054 1/20 0.42
CA2 P00918 3/20 0.41
ACE P12821 2/20 0.41
MEN1 O00255 1/20 0.41
AKR1C3 P42330 2/20 0.41
CYP2C19 P33261 1/20 0.41
CA1 P00915 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1633550 0.85
SCHEMBL199063 0.85
SCHEMBL199062 0.85
SCHEMBL27685893 0.83 ACE (0.46) ACECYP2C19
Hydrochloric Acid SCHEMBL28366662 0.83 ACE (0.46) ACECYP2C19
SCHEMBL27685894 0.83 ACE (0.46) ACECYP2C19
Ammonia Solution, Strong SCHEMBL27857098 0.83 ACE (0.46) ACECYP2C19
Hydrochloric Acid SCHEMBL28366660 0.83 ACE (0.46) ACECYP2C19
SCHEMBL9609487 0.79 MCL1 (0.44) ALDH1A1SMN1; SMN2
SCHEMBL2399501 0.79 ACE (0.42) ALDH1A1SMN1; SMN2ACECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5969114-A DISAZO DYES FOR BLACK COLOR INK JET PRINT ZENECA LIMITED (GB) 1999-10-19 US disclosed
EP-0888407-A1 AZO COMPOUND ZENECA LIMITED (GB) 1999-01-07 EP disclosed
WO-1997032932-A1 AZO COMPOUND ZENECA LIMITED (GB) 1997-09-12 WO disclosed