Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 8/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370695 | 0.91 | HSD17B2 (0.46) | HSD17B2TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL29771924 | 0.84 | TAS1R3 (0.67) | HSD17B2TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL22501503 | 0.83 | TAS1R3 (0.53) | HSD17B2TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL13860022 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2HTTMEN1 | |
| SCHEMBL28677650 | 0.82 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2HTTMEN1 | |
| SCHEMBL12234387 | 0.80 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2HTTMEN1 | |
| Hydrochloric Acid SCHEMBL29771914 | 0.79 | CA1 (0.54) | HSD17B2LIPGALDH1A1CA1CA2 | |
| SCHEMBL8516525 | 0.78 | KMT2A (0.56) | TAS1R3TAS1R1TAS1R2HTTMEN1 | |
| SCHEMBL14627425 | 0.77 | TAS1R3 (0.50) | HSD17B2TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL13857734 | 0.76 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052857-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 1999-10-21 | — | — | WO | disclosed |