Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.83 |
| ▸ | MAPT | P10636 | 8/20 | 0.83 |
| ▸ | LMNA | P02545 | 4/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | HTT | P42858 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
| ▸ | DDX3X | O00571 | 2/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | PYGL | P06737 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367419 | 0.91 | KMT2A (1.00) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL18825674 | 0.91 | KMT2A (1.00) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL1462371 | 0.83 | P2RX1 (0.68) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3678982 | 0.83 | MEN1 (0.67) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL16441842 | 0.83 | P2RX1 (0.71) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8371782 | 0.82 | GRIK1 (0.65) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8368364 | 0.82 | MEN1 (0.81) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3459824 | 0.82 | KMT2A (1.00) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL6431552 | 0.81 | GRIK1 (0.73) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL22092648 | 0.81 | MAPT (0.82) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910358-A1 | PHENYL DERIVATIVES USEFUL AS BLOCKERS OF CHLORIDE CHANNELS | NEUROSEARCH A/S (DK) | 1999-04-28 | — | — | EP | disclosed |
| EP-0693053-B1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 1999-01-20 | — | — | EP | disclosed |
| US-5696138-A | Urea derivatives and their use | NEUROSEARCH A/S (DK) | 1997-12-09 | — | — | US | disclosed |
| WO-1997045111-A1 | PHENYL DERIVATIVES USEFUL AS BLOCKERS OF CHLORIDE CHANNELS | NEUROSEARCH A/S (DK) | 1997-12-04 | — | — | WO | disclosed |
| EP-0693053-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022807-A1 | UREA AND AMIDE DERIVATIVES AND THEIR USE IN THE CONTROL OF CELL MEMBRANE POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 1994-10-13 | — | — | WO | disclosed |