SCHEMBL8370720

SCHEMBL8370720

Cc1cc(CCC(c2cc(C)c(O)c(C)c2)c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.47
PTGS2 P35354 5/20 0.47
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
HMGB1 P09429 1/20 0.39
CXCL12 P48061 1/20 0.39
SHBG P04278 1/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
NR3C1 P04150 1/20 0.35
PGR P06401 1/20 0.35
NR3C2 P08235 1/20 0.35
TTR P02766 3/20 0.33
ALOX5 P09917 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1596134 0.85 CA1 (0.48) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL10366947 0.82 PTGS1 (0.46) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL10834423 0.82 PTGS1 (0.46) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL1597151 0.81 CA1 (0.44) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL1517505 0.79 PTGS1 (0.43) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL23854324 0.79 CA1 (0.42) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL7202914 0.79 ESR1 (0.43) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL10430109 0.79 CA1 (0.42) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL10430054 0.79 CA1 (0.42) PTGS1PTGS2CA1CA2HMGB1
SCHEMBL4633834 0.79 PTGS1 (0.50) PTGS1PTGS2CA1CA2HMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0147759-B2 Latex containing odor inhibitors GOODRICH CO B F (US) 1999-05-06 EP disclosed
US-4759978-A Reaction product of a compound having three phenolic hydroxyl groups in a molecule, bisphenol epoxy resin and halogen containing epoxy resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-07-26 US disclosed
EP-0218439-A2 Epoxy resin composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-04-15 EP disclosed
US-4617230-A AMINE-TYPE ANTIOXIDANTS, HINDERED PHENOLS; CELLULOSE BONDED WITH LATEX, ACRYLATE MONOMERS THE B. F. GOODRICH COMPANY (US) 1986-10-14 US disclosed
EP-0147759-A2 Latex containing odor inhibitors The B.F. GOODRICH Company (US) 1985-07-10 EP disclosed
EP-0104644-A2 Polymeric composition containing diazabicycloalkanes The B.F. GOODRICH Company (US) 1984-04-04 EP disclosed
US-4439589-A ENOL ETHER AS MOLECULAR WEIGHT REGULATOR BAYER AKTIENGESELLSCHAFT (DE) 1984-03-27 US disclosed
US-RE31343-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
US-RE31342-E STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-08-09 US disclosed
EP-0036136-B1 PROCESS FOR PREPARING COPOLYMERS OF STYRENE AND/OR OF ITS DERIVATIVES BAYER AG (DE) 1983-04-13 EP disclosed
US-4067848-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4051137-A Substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1977-09-27 US disclosed
US-4028334-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1977-06-07 US disclosed
US-4007156-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-4007157-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1977-02-08 US disclosed
US-3992351-A ULTRAVIOLET RADIATION CIBA-GEIGY CORPORATION (US) 1976-11-16 US disclosed
US-3969316-A 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-13 US disclosed
US-3968078-A Alkyl alkanoate derivatives of substituted piperazine-diones and polymer compositions stabilized thereby CIBA-GEIGY CORPORATION (US) 1976-07-06 US disclosed
US-3937711-A POLYMERIC STABILIZERS, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-02-10 US disclosed
US-3936456-A Substituted piperazine dione oxyls and hydroxides and polymer compositions stabilized thereby CIBY-GEIGY CORPORATION (US) 1976-02-03 US disclosed