SCHEMBL7202914

SCHEMBL7202914

CCCC(c1cc(C)c(O)c(C)c1)c1cc(C)c(O)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.43
ESR2 Q92731 2/20 0.43
TP53 P04637 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
ALOX15 P16050 1/20 0.43
CYP2C19 P33261 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
PTGS1 P23219 5/20 0.35
PTGS2 P35354 5/20 0.35
ALOX5 P09917 2/20 0.35
TTR P02766 1/20 0.35
HMGB1 P09429 1/20 0.33
CXCL12 P48061 1/20 0.33
NQO1 P15559 1/20 0.33
HKDC1 Q2TB90 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP17A1 P05093 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1596134 0.89 CA1 (0.48) ESR1ESR2CYP2D6CYP2C9CA1
SCHEMBL9573429 0.88 ESR1 (0.43) ESR1ESR2TP53CYP2D6CYP2C9
SCHEMBL10456511 0.87 ALOX15 (0.41) ESR1ESR2TP53CYP2D6CYP2C9
SCHEMBL16774473 0.86 ESR1 (0.42) ESR1ESR2CA1CA2PTGS1
SCHEMBL1597151 0.84 CA1 (0.44) ESR1ESR2CYP2D6CYP2C9CA1
SCHEMBL20520221 0.84 ESR1 (0.45) ESR1ESR2CA1CA2
SCHEMBL20520248 0.84 ESR1 (0.45) ESR1ESR2CA1CA2
SCHEMBL20520281 0.84 ESR1 (0.45) ESR1ESR2CA1CA2
SCHEMBL20520192 0.84 ESR1 (0.45) ESR1ESR2CA1CA2
SCHEMBL20520289 0.84 ESR1 (0.45) ESR1ESR2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767338-B2 3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers BASF SE (DE) 2023-09-26 US disclosed
US-20210253617-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS BASF SCHWEIZ AG (CH) 2021-08-19 US disclosed
US-6603035-B1 A method for producing a high purity cyanate comprising reacting a phenol compound represented by the following formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-05 US disclosed
US-6114487-A COATING AGENT, MOLDING MATERIAL, IMPROVED MOLD RELEASE DOW CORNING TORAY SILICONE CO., LTD. (JP) 2000-09-05 US disclosed
EP-0719812-B1 Copolycarbonate GEN ELECTRIC (US) 1999-10-06 EP disclosed
US-5880248-A COPOLYCARBONATE DERIVED FROM TWO OR MORE AROMATIC DIHYDROXY COMPOUNDS AND A REACTION PRODUCT OF AN EPOXY COMPOUND WITH AN ACIDIC COMPOUND; IMPROVED IMPACT AND THERMAL RESISTANCE AND TRANSPARENCY GENERAL ELECTRIC COMPANY (US) 1999-03-09 US disclosed
US-5859172-A POLYCARBONATE MADE FROM SPECIFIED MONOMER ADMIXED WITH AN ACIDIC COMPOUND AND AN EPOXY COMPOUND; HARDNESS GENERAL ELECTRIC COMPANY (US) 1999-01-12 US disclosed
US-5646233-A HAVING OUTSTANDING HARDNESS GENERAL ELECTRIC COMPANY (US) 1997-07-08 US disclosed
EP-0507141-B1 Compatible blends of aromatic poly-(ester)-carbonates and polyamides BAYER AG (DE) 1997-04-23 EP disclosed
EP-0719812-A2 Copolycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed
US-5254624-A Molding materials BAYER AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
EP-0507141-A2 Compatible blends of aromatic poly-(ester)-carbonates and polyamides BAYER AG (DE) 1992-10-07 EP disclosed
EP-0503352-A2 Sulfonamide-groups containing polymers as compatibilizing agents for polyamide-polycarbonate blends BAYER AG (DE) 1992-09-16 EP disclosed
EP-0457103-A1 Mixtures of polyamides with aromatic (co)poly(ester)-carbonates based on tertiary alkyl ester groups containing bisphenols BAYER AG (DE) 1991-11-21 EP disclosed
EP-0368104-A2 Thermoplastic polyester carbonate polysiloxane block copolymers BAYER AG (DE) 1990-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253617-A1 3-PHENYL-BENZOFURAN-2-ONE DIPHOSPHATE DERIVATIVES AS STABILIZERS DHPS, PIR, NQO1 ESR1 1158/4885ESR2 2292/4885TP53 1383/4885
US-11767338-B2 3-phenyl-benzofuran-2-one diphosphate derivatives as stabilizers DHPS, PIR, NQO1 ESR1 1158/4885ESR2 2292/4885TP53 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.