Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061037 | 0.89 | DPP7 (0.36) | PPARGTYRSPHK1PRKCA | |
| SCHEMBL25426088 | 0.81 | PRKCA (0.36) | PPARGTYRNFKB1NFKB2RELA | |
| SCHEMBL258172 | 0.81 | — | — | |
| SCHEMBL21300 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA | |
| SCHEMBL15618384 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA | |
| SCHEMBL353470 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA | |
| SCHEMBL14915686 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA | |
| SCHEMBL1797486 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA | |
| SCHEMBL15618662 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA | |
| SCHEMBL5606129 | 0.79 | TSHR (0.44) | PPARGNFKB1NFKB2RELAPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925653-A | INSECTICIDES, ACARICIDES AND FUNGICIDES FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES IN THE FIELD OF VETERINARY MEDICINE | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-20 | — | — | US | disclosed |
| EP-0719259-B1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1999-01-20 | — | — | EP | disclosed |
| US-5595992-A | Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-21 | — | — | US | disclosed |
| EP-0719259-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007894-A1 | SUBSTITUTED PYRIDINES AND PYRIMIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |