Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 5/20 | 0.51 |
| ▸ | CACNA1D | Q01668 | 5/20 | 0.51 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400360 | 0.85 | CYP1A2 (0.64) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29926641 | 0.85 | CYP1A2 (0.64) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7448031 | 0.85 | CYP1A2 (0.64) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7400532 | 0.83 | CYP1A2 (0.46) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10469171 | 0.80 | CYP1A2 (0.58) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7285953 | 0.78 | MEN1 (0.79) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20801670 | 0.78 | CYP1A2 (0.55) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3118873 | 0.77 | CYP1A2 (0.44) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11012400 | 0.75 | MEN1 (0.63) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11802487 | 0.75 | NR1I2 (0.65) | MEN1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521310-B1 | Solid dispersion tablets containing 1,4-dihydropyridine derivatives and process for the preparation thereof | FUJIREBIO KK (JP) | 1999-01-20 | — | — | EP | disclosed |
| EP-0521310-A2 | Solid dispersion tablets containing 1,4-dihydropyridine derivatives and process for the preparation thereof | FUJIREBIO Inc. (JP) | 1993-01-07 | — | — | EP | disclosed |