Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 8/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 8/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 8/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 8/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370860 | 0.83 | MEN1 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL3118873 | 0.81 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL20801670 | 0.73 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL10469171 | 0.72 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL29926641 | 0.71 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL7448031 | 0.71 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL7400360 | 0.71 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL5537883 | 0.71 | LMNA (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL9721432 | 0.70 | MEN1 (0.63) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL7285953 | 0.68 | MEN1 (0.79) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555302-A1 | METHOD OF TREATING DEMYELINATING DISEASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007564-A2 | METHOD OF TREATING DEMYELINATING DISEASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-05-14 | — | — | WO | disclosed |