⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745018 | 0.77 | MAPT (0.34) | — | |
| SCHEMBL6840355 | 0.74 | — | — | |
| SCHEMBL22659278 | 0.74 | — | — | |
| SCHEMBL16464087 | 0.71 | HTR2B (0.39) | — | |
| SCHEMBL10865373 | 0.69 | CHRM2 (0.33) | — | |
| SCHEMBL461605 | 0.63 | — | — | |
| SCHEMBL11320926 | 0.62 | — | — | |
| SCHEMBL6507465 | 0.61 | — | — | |
| SCHEMBL4422176 | 0.61 | — | — | |
| Bromide SCHEMBL19681460 | 0.61 | SMN1; SMN2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116966178-B | Application of amino nitrothiazole derivative in preparation of medicine for preventing and treating virus infection and related diseases caused by virus infection | 成都贝诺科成生物科技有限公司 | 2025-10-03 | — | — | CN | disclosed |
| US-20250241901-A1 | ACTIVATION OF MNRR1 / CHCHD2 AS A THERAPEUTIC TARGET FOR MITOCHONDRIA ASSOCIATED DISORDERS | WAYNE STATE UNIVERSITY (US) | 2025-07-31 | — | — | US | disclosed |
| CN-116966178-A | Application of amino nitrothiazole derivative in preparation of medicine for preventing and treating virus infection and related diseases caused by virus infection | 成都贝诺科成生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116966178-A | Application of amino nitrothiazole derivative in preparation of medicine for preventing and treating virus infection and related diseases caused by virus infection | 成都贝诺科成生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2023198095-A1 | USE OF NITROTHIAZOLE DERIVATIVE IN PREPARING BACTERIOSTAT FOR INHIBITING HELICOBACTER PYLORI | 成都贝诺科成生物科技有限公司 | 2023-10-19 | — | — | WO | disclosed |
| EP-3081214-A2 | INHIBITORS OF CELLULAR NECROSIS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-2384753-B1 | Hydantoin derivatives as inhibitors of cellular necrosis | BRIGHAM & WOMENS HOSPITAL (US) | 2016-01-06 | — | — | EP | disclosed |
| US-8741942-B2 | Inhibitors of cellular necrosis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120149702-A1 | INHIBITORS OF CELLULAR NECROSIS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-8143300-B2 | Inhibitors of cellular necrosis | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-03-27 | — | — | US | disclosed |
| US-20040131628-A1 | Nucleic acids for the treatment of disorders associated with microorganisms | BRATZLER ROBERT L (US) | 2004-07-08 | — | — | US | disclosed |
| US-20040053208-A1 | Methods to selectively inactivate parasites in biological compositions | V. I. TECHNOLOGIES, Inc. (US) | 2004-03-18 | — | — | US | disclosed |
| WO-2003066806-A2 | THERAPEUTIC USE OF AZIRIDINO COMPOUNDS | V.I. TECHNOLOGIES, INC. (US) | 2003-08-14 | — | — | WO | disclosed |
| WO-2003047602-A1 | IMMUNOSTIMULATORY OLIGODEOXYNUCLEOTIDES | INTERCELL AG (AT) | 2003-06-12 | — | — | WO | disclosed |
| US-20020091097-A1 | Nucleic acids for the prevention and treatment of sexually transmitted diseases | COLEY PHARMACEUTICAL GROUP, INC. | 2002-07-11 | — | — | US | disclosed |
| EP-1077708-A1 | METHODS FOR THE PREVENTION AND TREATMENT OF PARASITIC INFECTIONS AND RELATED DISEASES USING CPG OLIGONUCLEOTIDES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999056755-A1 | METHODS FOR THE PREVENTION AND TREATMENT OF PARASITIC INFECTIONS AND RELATED DISEASES USING CPG OLIGONUCLEOTIDES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1999-11-11 | — | — | WO | disclosed |
| US-5652344-A | 2-amino-5-nitrothiazole derived monoazo disperse dyes | ALLIED INDUSTRIAL CORP., LTD. (TW) | 1997-07-29 | — | — | US | disclosed |
| EP-0051818-B1 | PROCESS FOR THE PRODUCTION OF DISCHARGE-RESIST PRINTS ON TEXTILE MATERIALS | CASSELLA Aktiengesellschaft (DE) | 1985-09-04 | — | — | EP | disclosed |
| US-4218478-A | Trichostatin as an antiprotozoal agent | OIWA RUIKO | 1980-08-19 | — | — | US | disclosed |