SCHEMBL8371765

SCHEMBL8371765

CS(=O)(=O)c1cc([N+](=O)[O-])ccc1N=Nc1ccc(OP(=O)(O)O)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ MAPT P10636 2/20 0.43
▸ PRMT1 Q99873 1/20 0.39
▸ HPGD P15428 3/20 0.38
▸ CYP1A2 P05177 3/20 0.38
▸ CYP2C9 P11712 3/20 0.38
▸ HSD17B10 Q99714 3/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ TSHR P16473 2/20 0.38
▸ ALOX15 P16050 2/20 0.38
▸ CYP2C19 P33261 2/20 0.38
▸ CYP2D6 P10635 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ CSNK2A1 P68400 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ APEX1 P27695 2/20 0.36
▸ TBXA2R P21731 5/20 0.35
▸ PTGS2 P35354 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL10869622 0.84 MAPT (0.47) MEN1KMT2AMAPTPRMT1HPGD
SCHEMBL16285337 0.75 MAPT (0.47) MEN1KMT2AMAPTPRMT1HPGD
SCHEMBL10746715 0.74 KMT2A (0.38) MEN1KMT2AMAPTHPGDCYP1A2
SCHEMBL10349172 0.73 MEN1 (0.49) MEN1KMT2AMAPTHPGDHSD17B10
SCHEMBL10745127 0.73 MEN1 (0.41) MEN1KMT2AMAPTHSD17B10CYP3A4
SCHEMBL10582840 0.73 MEN1 (0.43) MEN1KMT2AMAPTPRMT1HSD17B10
SCHEMBL10583716 0.73 MEN1 (0.43) MEN1KMT2AMAPTPRMT1HSD17B10
SCHEMBL9350534 0.72 CYP19A1 (0.48) MEN1KMT2AMAPTHPGDCYP1A2
SCHEMBL9350540 0.72 CYP19A1 (0.48) MEN1KMT2AMAPTHPGDCYP1A2
SCHEMBL9625069 0.71 MEN1 (0.60) MEN1KMT2AMAPTHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0258035-B1 ANALYTICAL ELEMENT AND METHOD FOR THEOPHYLLINE DETERMINATION HAVING INCREASED ALKALINE PHOSPHATASE ISOENZYME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-06-03 — — EP claimed
EP-0188372-B1 ANALYTICAL ELEMENT, COMPOSITION, KIT AND METHOD FOR DETERMINATION OF THEOPHYLLINE BY ENZYME INHIBITION EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-01-02 — — EP claimed
US-5028528-A Containing An Isoenzyme Of Alkaline Phosphatase EASTMAN KODAK COMPANY (US) 1991-07-02 — — US claimed
EP-0353026-A2 Analytical element for theophylline determination using buffer in a subbing zone EASTMAN KODAK COMPANY (US) 1990-01-31 — — EP claimed
US-4806470-A LESS INTERFERENCE FROM ENDOGENOUS PHOSPHATASE AND HEMOGLOBINS EASTMAN KODAK COMPANY (US) 1989-02-21 — — US claimed
US-4782017-A Analytical element and method for determination of theophylline by enzyme inhibition EASTMAN KODAK COMPANY (US) 1988-11-01 — — US claimed
US-4782016-A ISOENZYME OF ALKALINE PHOSPHATASE EASTMAN KODAK COMPANY (US) 1988-11-01 — — US claimed
EP-0258035-A2 Analytical element and method for theophylline determination having increased alkaline phosphatase isoenzyme EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-02 — — EP claimed
US-5981206-A STORAGE STABLE DIAGNOSTIC ELEMENT OF ACIDIC BUFFER, NONHYGROSCOPIC ALKALINE EARTH METAL SALT OF AN ARYL PHOSPHATE ESTER, AND A DIAZONIUM OR TETRAZOLIUM SALT JOHNSON & JOHNSON CLINICAL DIAGNOSTIC SYSTEMS, INC. (US) 1999-11-09 — — US disclosed
EP-0574056-B1 Dry analytical element for the detection of prostatic acid phosphatase JOHNSON & JOHNSON CLIN DIAG (US) 1999-02-10 — — EP disclosed
EP-0574056-A1 Dry analytical element for the detection of prostatic acid phosphatase Johnson & Johnson Clinical Diagnostics, Inc. (US) 1993-12-15 — — EP disclosed
EP-0258034-B1 ANALYTICAL ELEMENT AND METHOD FOR THEOPHYLLINE DETERMINATION USING BUFFER IN SPREADING ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-06-03 — — EP disclosed
EP-0258035-B1 ANALYTICAL ELEMENT AND METHOD FOR THEOPHYLLINE DETERMINATION HAVING INCREASED ALKALINE PHOSPHATASE ISOENZYME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-06-03 — — EP disclosed
EP-0188372-B1 ANALYTICAL ELEMENT, COMPOSITION, KIT AND METHOD FOR DETERMINATION OF THEOPHYLLINE BY ENZYME INHIBITION EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-01-02 — — EP disclosed
EP-0353026-A2 Analytical element for theophylline determination using buffer in a subbing zone EASTMAN KODAK COMPANY (US) 1990-01-31 — — EP disclosed
US-4806470-A LESS INTERFERENCE FROM ENDOGENOUS PHOSPHATASE AND HEMOGLOBINS EASTMAN KODAK COMPANY (US) 1989-02-21 — — US disclosed
US-4782016-A ISOENZYME OF ALKALINE PHOSPHATASE EASTMAN KODAK COMPANY (US) 1988-11-01 — — US disclosed
US-4782017-A Analytical element and method for determination of theophylline by enzyme inhibition EASTMAN KODAK COMPANY (US) 1988-11-01 — — US disclosed
EP-0258035-A2 Analytical element and method for theophylline determination having increased alkaline phosphatase isoenzyme EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-02 — — EP disclosed
EP-0258034-A2 Analytical element and method for theophylline determination using buffer in spreading zone EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-02 — — EP disclosed
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