Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645111 | 0.85 | PRMT1 (0.57) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL8371765 | 0.84 | MEN1 (0.43) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11169265 | 0.83 | APEX1 (0.41) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11777648 | 0.83 | APEX1 (0.41) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL10882817 | 0.82 | PHLPP2 (0.47) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11775618 | 0.82 | ATIC (0.48) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11775610 | 0.82 | ATIC (0.48) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11152358 | 0.81 | APEX1 (0.50) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11152363 | 0.81 | PHLPP2 (0.47) | MAPTMEN1KMT2APRMT1GLO1 | |
| SCHEMBL11152362 | 0.81 | APEX1 (0.50) | MAPTMEN1KMT2APRMT1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188372-A2 | Analytical element, composition, kit and method for determination of theophylline by enzyme inhibition | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-23 | — | — | EP | claimed |
| EP-0188372-A2 | Analytical element, composition, kit and method for determination of theophylline by enzyme inhibition | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-23 | — | — | EP | disclosed |