Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL30865453 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1302105 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28197463 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL31511815 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1938072 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28651927 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28354172 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL11065189 | 0.97 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL3231 | 0.97 | — | — | |
| Aspartic Acid SCHEMBL11065185 | 0.97 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110124042-A | Aluminum-free composition for inhibiting bromhidrosis | 赵叶莲 | 2019-08-16 | — | — | CN | claimed |
| CN-109589298-A | A kind of artemia eggs ghost dispersion liquid and its preparation process and application | 水母娘娘海洋生物科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-109548950-A | The polypeptide and its preparation process in a kind of aurelia source and application | 水母娘娘海洋生物科技有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-108887479-A | L-Aspartic acid zinc promotes animal intestinal tract development in preparation and alleviates the application in intestinal tract injury preparation | 华南农业大学 | 2018-11-27 | — | — | CN | claimed |
| CN-108853139-A | The medical composition and its use of various trace elements VII | 刘力 | 2018-11-23 | — | — | CN | claimed |
| CN-108218588-A | biological humic acid water-soluble fertilizer | 湖北吾尔利生物工程股份有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-107468572-A | One kind polishing isolation breast and preparation method thereof | 漳浦彩露华化妆品有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-107049803-A | Use catechol, manganese salt or zinc salt, hydrogen peroxide, carbonic acid（Hydrogen）The hair-dyeing method of salt, basifier and titanium salt or scandium salts | 欧莱雅 | 2017-08-18 | — | — | CN | claimed |
| CN-106170518-A | HYDROGEN SULFIDE SCAVENGER | 伊诺弗斯公司 | 2016-11-30 | — | — | CN | claimed |
| CN-105623525-A | Efficient metal polishing liquid | FANCHANG COUNTY CHENSHI METAL PRODUCTS CO LTD | 2016-06-01 | — | — | CN | claimed |
| CN-101431976-A | Composition for dyeing keratin fibers and a method of dyeing hair using same | ADVANCE COSMETIC TECHNOLOGIES (US) | 2009-05-13 | — | — | CN | claimed |
| CN-101239925-A | Method for preparing magnesium aspartate | BEIJING JINGWEI XINKANG PHARMA (CN) | 2008-08-13 | — | — | CN | claimed |
| CN-101234992-A | Method for preparing aspartic acid | BEIJING JINGWEI XINGKANG PHARM (CN) | 2008-08-06 | — | — | CN | claimed |
| CN-1305467-C | Zinc-containing compositions for antiviral use | SMITH J B (US) | 2007-03-21 | — | — | CN | claimed |
| CN-1832726-A | Aqueous pharmaceutical solution containing oxymetazoline and/or xylometazoline | MERCK PATENT GMBH (DE) | 2006-09-13 | — | — | CN | claimed |
| CN-1720249-A | Preparation method of amino acid chelate | MD BIOALPHA CO LTD (KR) | 2006-01-11 | — | — | CN | claimed |
| CN-1533272-A | Zinc-containing compositions for antiviral use | J��B��ʷ��˹ | 2004-09-29 | — | — | CN | claimed |
| CN-1166963-A | Composition containing zinc compound and p-acetaminophenyl acetic acid | XIA XIAOLIN (CN) | 1997-12-10 | — | — | CN | claimed |
| CN-1166320-A | Composite of zinc containing compound and glutamines | XIA XIAOLIN (CN) | 1997-12-03 | — | — | CN | claimed |
| CN-1080526-A | Infect the Therapeutic Method of disease, the anti-corrosion method of cosmetics, antibiotic and antimycotic agent and cosmetics | OTSUKA PHARMA CO LTD (JP) | 1994-01-12 | — | — | CN | claimed |