Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370366 | 0.93 | ACHE (0.70) | ACHETDP1 | |
| SCHEMBL11848496 | 0.91 | ACHE (0.61) | ACHETDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL15686517 | 0.91 | ACHE (0.74) | ACHETDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30603265 | 0.89 | ACHE (0.76) | ACHETDP1 | |
| SCHEMBL2870052 | 0.88 | ACHE (0.80) | ACHE | |
| SCHEMBL5248874 | 0.88 | ACHE (0.86) | ACHE | |
| SCHEMBL21341289 | 0.87 | ACHE (0.79) | ACHETDP1 | |
| SCHEMBL12179746 | 0.86 | ACHE (0.62) | ACHETDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12990983 | 0.86 | ACHE (0.57) | ACHETDP1 | |
| SCHEMBL10717902 | 0.85 | ACHE (0.71) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3238738-B1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORP (CA) | 2020-09-23 | — | — | EP | disclosed |
| EP-2355851-B1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORP (CA) | 2018-04-04 | — | — | EP | disclosed |
| EP-3238738-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | Arbutus Biopharma Corporation (CA) | 2017-11-01 | — | — | EP | disclosed |
| WO-2010144740-A1 | IMPROVED LIPID FORMULATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010105209-A1 | LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| WO-2010054401-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010054405-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010054384-A1 | LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010042877-A1 | IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2010-04-15 | — | — | WO | disclosed |
| EP-0797611-B1 | ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT | KING INDUSTRIES INC (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0797611-A1 | ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT | Blank, Werner J. (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5565531-A | AUTOMOBILE PROTECTIVE TOPCOATINGS COMPRISING POLYURETHANES HAVING PENDANT ALKYL CHAINS CONTAINING AN ETHER MADE FROM A DICARBAMATE, POLYOL AND ETHER-CONTAINING CARBAMATE; WEATHERPROOFING; DURABILITY; SOLVENT SOLUBILITY | KING INDUSTRIES, INC. (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1995032999-A1 | ACID ETCH RESISTANT AUTOMOTIVE TOPCOAT | BLANK WERNER J (US) | 1995-12-07 | — | — | WO | disclosed |